Evidence map›Paper›PMID 32631218›Full record

SynthesisBMC immunology2020

Prognostic role of red blood cell distribution width in patients with sepsis: a systematic review and meta-analysis.

Lin Zhang, Cui-Hua Yu, Kuan-Peng Guo, Cai-Zhi Huang, Li-Ya Mo

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 6 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 6 syntheses or guidelines pooled it, 103 citations in OpenAlex.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lin ZhangDepartment of clinical laboratory, Hunan children's hospital, Changsha, China. ychxyeyy@sina.com.ORCID 0000-0001-5839-7002
Cui-Hua YuDepartment of GCP certified sites, The third hospital of Changsha City, Changsha, Hunan Province, China.
Kuan-Peng GuoDepartment of clinical laboratory, Hunan children's hospital, Changsha, China.
Cai-Zhi HuangDepartment of clinical laboratory, Hunan children's hospital, Changsha, China.
Li-Ya MoDepartment of clinical laboratory, Hunan children's hospital, Changsha, China.
Hunan Children's Hospital · CNThird Hospital of Changsha · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutcome prediction for patients with sepsis may be conductive to early aggressive interventions. Numerous biomarkers and multiple scoring systems have been utilized in predicting outcomes, however, these tools were either expensive or inconvenient. We performed a meta-analysis to evaluate the prognostic role of red blood cell distribution width (RDW) in patients with sepsis.

methodsThe online databases of Embase, Web of science, Pubmed, Corchrane library, Chinese Wanfang database, CNKI database were systematically searched from the inception dates to June, 24th, 2020, using the keywords red cell distribution width and sepsis. The odds ratio (OR) or Hazards ratio (HR) with corresponding 95% confidence intervals (95%CI) were pooled to evaluate the association between baseline RDW and sepsis. A random-effects model was used to pool the data, and statistical heterogeneity between studies was evaluated using the I

resultsEleven studies with 17,961 patients with sepsis were included in the meta-analysis. The pooled analyses indicated that increased baseline RDW was associated with mortality (HR = 1.14, 95%CI 1.09-1.20, Z = 5.78, P < 0.001) with significant heterogeneity (I

conclusionsFor patients with sepsis, baseline RDW may be a useful predictor of mortality, patients with increased RDW are more likely to have higher mortality.

Indexed as

BiomarkersErythrocyte IndicesErythrocytesHumansPredictive Value of TestsPrognosisSepsisSurvival AnalysisBiomarkersMeta-analysisMortalityRed cell distribution widthSepsisSeptic shock

Identifiers

PMID32631218
PMCPMC7339553
OpenAlexW3040282622

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.