SynthesisUnited European gastroenterology journal2020
The global prevalence of Barrett's esophagus: A systematic review of the published literature.
Synthesis in United European gastroenterology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors for the Development of Barrett's Esophagus and Esophageal Adenocarcinoma: A Systematic Review and Meta-Analysis.Cancer reports (Hoboken, N.J.) · 2025Pooled it
- Texture and Colour Enhancement Imaging versus White Light Endoscopy for Detection of Dysplasia within Barrett's Oesophagus: A Pilot Study.Digestion · 2026Trial
- Global incidence of esophageal cancer by histological and anatomical subtypes.Nature communications · 2026Article
- Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours.The Journal of pathology · 2026Review
- Endoscopic submucosal dissection for the treatment of early Barrett's neoplasia: long-term outcomes of a prospective multicenter study.Annals of gastroenterology · 2026Article
- Review
- Barrett's esophagus around the world: a systematic review and predictive modeling study.Gastroenterology and hepatology from bed to bench · 2026Review
- A Multidisciplinary, Digitally-Integrated Life-Cycle Management Model for Early Gastrointestinal Cancer: Enhancing Care Coordination and Continuity.Journal of multidisciplinary healthcare · 2026Review
- Barrett's esophagus: A review.World journal of gastrointestinal pathophysiology · 2025Review
- Prevalence of Barrett's esophagus and gastroesophageal reflux disease 5 years after laparoscopic sleeve gastrectomy: A retrospective study.World journal of gastrointestinal surgery · 2025Article
- Increased Prevalence of Barrett's Esophagus in Taiwan: A Prospective Multicenter Study.Journal of gastroenterology and hepatology · 2025Article
- Computing lifetime incidence of esophageal adenocarcinoma and age-specific prevalence of Barrett's esophagus.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025Article
- Review
- Population-specific characteristics and outcomes in esophageal neuroendocrine carcinoma: a Chinese-Western comparison with prognostic nomogram.Therapeutic advances in medical oncology · 2025Article
- Article
- Endoscopic assessment of failed fundoplications differs between endoscopists.Surgical endoscopy · 2024Article
- Cytosponge procedures produce fewer respiratory aerosols and droplets than esophagogastroduodenoscopies.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- Professionals' views on the justification for esophageal adenocarcinoma screening: A systematic literature search and qualitative analysis.Preventive medicine reports · 2023Review
- Gastroesophageal reflux disease incidence among male patients with irritable bowel syndrome: A single-center cross-sectional study in southern Iran.JGH open : an open access journal of gastroenterology and hepatology · 2023Article
- Length of the Barrett's Esophagus Is Proportional to the Abnormality of Esophageal Motility and Anti-reflux Barrier.Journal of neurogastroenterology and motility · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDetermining the prevalence of Barrett's esophagus is important for defining screening strategies. We aimed to synthesize the available data, determine Barrett's esophagus prevalence, and assess variability.
methodsThree databases were searched. Subgroup, sensitivity, and meta-regression analyses were conducted and pooled prevalence was computed.
resultsOf 3510 studies, 103 were included. In the general population, we estimated a prevalence for endoscopic suspicion of Barrett's esophagus of (a) any length with histologic confirmation of intestinal metaplasia as 0.96% (95% confidence interval: 0.85-1.07), (b) ≥1 cm of length with histologic confirmation of intestinal metaplasia as 0.96% (95% confidence interval: 0.75-1.18) and (c) for any length with histologic confirmation of columnar metaplasia as 3.89% (95% confidence interval: 2.25-5.54) . By excluding studies with high-risk of bias, the prevalence decreased to: (a) 0.70% (95% confidence interval: 0.61-0.79) and (b) 0.82% (95% confidence interval: 0.63-1.01). In gastroesophageal reflux disease patients, we estimated the prevalence with afore-mentioned criteria to be: (a) 7.21% (95% confidence interval: 5.61-8.81) (b) 6.72% (95% confidence interval: 3.61-9.83) and (c) 7.80% (95% confidence interval: 4.26-11.34). The Barrett's esophagus prevalence was significantly influenced by time period, region, Barrett's esophagus definition, Seattle protocol, and study design. There was a significant gradient East-West and North-South. There were minimal to no data available for several countries. Moreover, there was significant heterogeneity between studies.
conclusionThere is a need to reassess the true prevalence of Barrett's esophagus using the current guidelines in most regions. Having knowledge about the precise Barrett's esophagus prevalence, diverse attitudes from educational to screening programs could be taken.
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