ArticleOptics letters2020
High-speed fiber-optic scanning nonlinear endomicroscopy for imaging neuron dynamicsin vivo.
Article in Optics letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Focus-tunable two-photon fiberscope enablingOptics letters · 2025Article
- Alleviating head-mounted weight burden for neural imaging in freely-behaving rodents.Scientific reports · 2025Article
- Integrating Optics and Parametrically-Resonant Micro-Scanner Design for Large Working Distance Implantable Microscopy.IEEE/ASME transactions on mechatronics : a joint publication of the IEEE Industrial Electronics Society and the ASME Dynamic Systems and Control Division · 2025Article
- Video-rate two-photon microendoscopy using second harmonic resonance fiber scanning.Biomedical optics express · 2024Article
- Size and Illumination Matters: Local Magnetic Actuation and Fluorescence Imaging for Microrobotics.Journal of the Indian Institute of Science · 2024Review
- Two-photon microscopy for microrobotics: Visualization of micro-agents below fixed tissue.PloS one · 2023Article
- Label-free highly multimodal nonlinear endoscope.Optics express · 2022Article
- Multicolor fiber-optic two-photon endomicroscopy for brain imaging.Optics letters · 2021Article
- Label-free imaging of human brain tissue at subcellular resolution for potential rapid intra-operative assessment of glioma surgery.Theranostics · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Fiber-optic-based two-photon fluorescence endomicroscopy is emerging as an enabling technology for in vivo histological imaging of internal organs and functional neuronal imaging on freely-behaving animals. However, high-speed imaging remains challenging due to the expense of miniaturization and lack of suited fast beam scanners. For many applications, a higher imaging speed is highly desired, especially for monitoring functional dynamics such as transient dendritic responses in neuroscience. This Letter reports the development of a fast fiber-optic scanning endo-microscope with an imaging speed higher than 26 frames/s. In vivo neural dynamics imaging with the high-speed endomicroscope was performed on a freely-behaving mouse over the primary motor cortex that expressed GCaMP6m. The results demonstrate its capability of real-time monitoring of transient neuronal dynamics with very fine temporal resolution.
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