Evidence map›Paper›PMID 32630696›Full record

ArticleMolecules (Basel, Switzerland)2020

Biogenic Silver Nanoparticles: Assessment of Their Cytotoxicity, Genotoxicity and Study of Capping Proteins.

Magdalena Wypij, Tomasz Jędrzejewski, Maciej Ostrowski, Joanna Trzcińska, Mahendra Rai, Patrycja Golińska

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  5. Review
  6. AqueousNanomaterials (Basel, Switzerland) · 2025
    Article
  7. Rosmarinic Acid-RichMolecules (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Green Synthesis of Silver Nanoparticles usingPharmaceutical nanotechnology · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Magdalena WypijDepartment of Microbiology, Nicolaus Copernicus University, Lwowska 1, 87100 Torun, Poland.
Tomasz JędrzejewskiDepartment of Immunology, Nicolaus Copernicus University, Lwowska 1, 87100 Torun, Poland.ORCID 0000-0001-8950-5643
Maciej OstrowskiDepartment of Biochemistry, Nicolaus Copernicus University, Lwowska 1, 87100 Torun, Poland.
Joanna TrzcińskaDepartment of Microbiology, Nicolaus Copernicus University, Lwowska 1, 87100 Torun, Poland.
Mahendra RaiNanobiotechnology Lab., Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra 444602, India.
Patrycja GolińskaDepartment of Microbiology, Nicolaus Copernicus University, Lwowska 1, 87100 Torun, Poland.ORCID 0000-0001-9154-8191
Nicolaus Copernicus University · PLSant Gadge Baba Amravati University · IN

Funding

Narodowe Centrum Nauki 2016/23/N/NZ9/00247
6 · The paper itself

Abstract

The development of nanotechnology in the last two decades has led to the use of silver nanoparticles (AgNPs) in various biomedical applications, including antimicrobial, anti-inflammatory, and anticancer therapies. However, the potential of the medical application of AgNPs depends on the safety of their use. In this work, we assessed the in vitro cytotoxicity and genotoxicity of silver nanoparticles and identified biomolecules covering AgNPs synthesized from actinobacterial strain SH11. The cytotoxicity of AgNPs against MCF-7 human breast cancer cell line and murine macrophage cell line RAW 264.7 was studied by MTT assay, cell LDH (lactate dehydrogenase) release, and the measurement of ROS (reactive oxygen species) level while genotoxicity in

Indexed as

ActinobacteriaAnimalsBacterial ProteinsCytotoxinsDose-Response Relationship, DrugElectrophoresis, Polyacrylamide GelHumansL-Lactate DehydrogenaseMCF-7 CellsMetal NanoparticlesMiceMutagenicity TestsRAW 264.7 CellsReactive Oxygen SpeciesSalmonella typhimuriumSilverBacterial ProteinsCytotoxinsL-Lactate DehydrogenaseReactive Oxygen SpeciesSilverbiosynthesiscapping proteinscytotoxicitygenotoxicitysilver nanoparticles

Identifiers

PMID32630696
PMCPMC7412363
OpenAlexW3038967872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.