ReviewJournal of clinical medicine2020
Accuracy of Pulse Wave Velocity Predicting Cardiovascular and All-Cause Mortality. A Systematic Review and Meta-Analysis.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 7 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Comparative effectiveness of various exercise modalities on arterial stiffness and endothelial function in older adults: a systematic review and network meta-analysis of randomised controlled trials.Frontiers in cardiovascular medicine · 2026Pooled it
- Pooled it
- Comparative effectiveness of statins and exercise in high-risk individuals: systematic review and network meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Pooled it
- Association between arterial stiffness and orthostatic hypotension: A systematic review and meta-analysis.Frontiers in physiology · 2023Pooled it
- Pulse Wave Velocity and Sarcopenia in Older Persons-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Association Between Arterial Stiffness and Blood Pressure Progression With Incident Hypertension: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Classification of patients with Alzheimer's disease using the arterial pulse spectrum and a multilayer-perceptron analysis.Scientific reports · 2021Trial
- Improvement in Aortic Stiffness After 9 Months of Antiretroviral Therapy in Treatment-Naïve People Living with HIV.Diagnostics (Basel, Switzerland) · 2026Article
- Associations of C-Reactive Protein-Triglyceride Glucose Index and Estimated Pulse Wave Velocity With All-Cause Mortality: A Nationwide Prospective Cohort Study.Health science reports · 2026Article
- Article
- Article
- Relationship of Carotid-Femoral Pulse Wave Velocity and Brachial-Ankle Pulse Wave Velocity With the Risk of New-Onset Cardiovascular Events: A Cohort Study in the Beijing Community-Based Population.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Article
- Evaluation of Blood Flow Energy Loss before and after Endovascular Aneurysm Repair Using Four-dimensional Flow MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- Association Between Metabolic Syndrome Components and Vascular Structure and Function in Subjects with a Diagnosis of Long COVID: The BioICOPER Study.Journal of clinical medicine · 2026Article
- Characterizing the Clinical, Vascular, and Functional Phenotype of Metabolic Acidosis in Kidney Transplantation: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- The Emerging Role of Mechanobiology in Connecting Metabolic and Cardiovascular Diseases: From Fundamentals to Future Therapies.Biomedicines · 2026Review
- Effect of stent-graft length and compliance on aortic hemodynamics in a bench-top physiological flow circuit.Journal of the mechanical behavior of biomedical materials · 2026Article
- Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
Abstract
Increased arterial stiffness has been associated with an increased risk of developing cardiovascular diseases and all-cause mortality. Pulse wave velocity (PWV) is an innovative and affordable measurement of arterial stiffness which may be an accessible tool to estimate mortality risk; however, no meta-analysis has estimated its predictive performance for cardiovascular and all-cause mortality. Moreover, reference values for PWV have only been established by consensus for healthy populations. The aim of this review was to estimate PWV and especially carotid femoral PWV performance predicting cardiovascular and all-cause mortality as well as comparing the resulting cfPWV thresholds with already established values in order to increase its validity. Original studies measuring PWV thresholds and its association with cardiovascular and all-cause mortality were systematically searched. The DerSimonian and Laird method was used to compute pooled estimates of diagnostic odds ratio (dOR), and overall test performances were summarized in hierarchical summary receiver operating characteristic curves (HSROC). Six studies were included in the meta-analysis. The pooled dOR values for the predictive performance of cfPWV were 11.23 (95 % CI, 7.29-1.29) for cardiovascular mortality and 6.52 (95% CI, 4.03-10.55) for all-cause mortality. The area under the HSROC curve for cfPWV was 0.75 (95% CI, 0.69-0.81) for cardiovascular mortality and 0.78 (95% CI, 0.74-0.83) for all-cause mortality, where the closest cut-off point to the summary point was 10.7 and 11.5, respectively. This systematic review and meta-analysis demonstrates that cfPWV is a useful and accurate cardiovascular mortality predictor and that its previously estimated reference values for estimating risk may be used in high-risk populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.