Evidence map›Paper›PMID 32630594›Full record

ArticleMolecules (Basel, Switzerland)2020

Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of

Edward Krzyżak, Dominika Szkatuła, Benita Wiatrak, Tomasz Gębarowski, Aleksandra Marciniak

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Anti-Inflammatory Activity of Cyclic Imide Derivatives.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Interactions ofMembranes · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. A New N-Substituted 1International journal of molecular sciences · 2021
    Article
  11. An Overview of the Biological Activity of Pyrrolo[3,4-Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  12. Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-International journal of molecular sciences · 2020
    Article
  13. Bioresearch of New 1Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edward KrzyżakDepartment of Inorganic Chemistry, Wroclaw Medical University, ul. Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0002-5000-2448
Dominika SzkatułaDepartment of Medicinal Chemistry, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0002-6543-4753
Benita WiatrakDepartment of Basic Medical Sciences, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0002-1404-2274
Tomasz GębarowskiDepartment of Basic Medical Sciences, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland.ORCID 0000-0002-8742-0790
Aleksandra MarciniakDepartment of Inorganic Chemistry, Wroclaw Medical University, ul. Borowska 211a, 50-556 Wrocław, Poland.ORCID 0000-0003-2225-7897

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego 016/RID/2018/19
6 · The paper itself

Abstract

Inhibition of cyclooxygenase is the way of therapeutic activities for anti-inflammatory pharmaceuticals. Serum albumins are the major soluble protein able to bind and transport a variety of exogenous and endogenous ligands, including hydrophobic pharmaceuticals. In this study, a novel

Indexed as

Binding SitesCells, CulturedCyclooxygenase 1Cyclooxygenase 2Cyclooxygenase InhibitorsDermisFibroblastsFluorescenceHumansLigandsMolecular Docking SimulationSerum Albumin, BovineThermodynamicsCyclooxygenase 1Cyclooxygenase 2Cyclooxygenase InhibitorsLigandsPTGS1 protein, humanPTGS2 protein, humanSerum Albumin, Bovineanti-inflammatorycyclooxygenasefluorescence quenchingmolecular dockingpyrrolo-pyridine derivativesserum albumin interactions

Identifiers

PMID32630594
PMCPMC7355801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.