Evidence map›Paper›PMID 32630544›Full record

ArticleJournal of clinical medicine2020

Impaired Fibrinolysis in Patients with Isolated Aortic Stenosis is Associated with Enhanced Oxidative Stress.

Jakub Siudut, Joanna Natorska, Ewa Wypasek, Łukasz Wiewiórka, Elżbieta Ostrowska-Kaim, Sylwia Wiśniowska-Śmiałek, Krzysztof Plens, Jacek Legutko, Anetta Undas

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Fibrin clot properties and thrombus composition in cirrhosis.Research and practice in thrombosis and haemostasis · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. A ModifiedFrontiers in neurology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jakub SiudutInstitute of Cardiology, Jagiellonian University Medical College, 31-202 Krakow, Poland.ORCID 0000-0001-9776-440X
Joanna NatorskaInstitute of Cardiology, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Ewa WypasekFaculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, 30-705 Krakow, Poland.
Łukasz WiewiórkaDepartment of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, Poland.
Elżbieta Ostrowska-KaimDepartment of Interventional Cardiology, John Paul II Hospital, 31-202 Krakow, Poland.
Sylwia Wiśniowska-ŚmiałekDepartment of Cardiac and Vascular Diseases, John Paul II Hospital, 31-202 Krakow, Poland.
Krzysztof PlensKCRI, 30-055 Krakow, Poland.
Jacek LegutkoInstitute of Cardiology, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Anetta UndasInstitute of Cardiology, Jagiellonian University Medical College, 31-202 Krakow, Poland.
Jagiellonian University · PLJohn Paul II Hospital · PLAndrzej Frycz Modrzewski Krakow University · PLKrakow Cardiovascular Research Institute · PL

Funding

Narodowe Centrum Nauki UMO-2016/21/N/NZ5/00512
6 · The paper itself

Abstract

Aortic stenosis (AS) has been associated with impaired fibrinolysis and increased oxidative stress. This study aimed to investigate whether oxidative stress could alter fibrin clot properties in AS. We studied 173 non-diabetic patients, aged 51-79 years, with isolated AS. We measured plasma protein carbonylation (PC) and thiobarbituric acid reactive substances (TBARS), along with plasma clot permeability (K

Indexed as

aortic stenosisfibrinolysisoxidative stressPAI-1α2-antiplasmin

Identifiers

PMID32630544
PMCPMC7355626
OpenAlexW3037923412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.