Evidence map›Paper›PMID 32630542›Full record

ArticleCancers2020

Integrated Assessment of Circulating Cell-Free MicroRNA Signatures in Plasma of Patients with Melanoma Brain Metastasis.

Matias A Bustos, Kevin D Tran, Negin Rahimzadeh, Rebecca Gross, Selena Y Lin, Yoshiaki Shoji, Tomohiro Murakami, Christine L Boley, Linh T Tran, Hunter Cole and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  10. The role of microRNAs in brain metastasis.Journal of neuro-oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Matias A BustosDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.ORCID 0000-0001-9625-1127
Kevin D TranDepartment of Genomic Sequencing Center, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.
Negin RahimzadehDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.ORCID 0000-0002-7797-620X
Rebecca GrossDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.ORCID 0000-0002-1175-5789
Selena Y LinDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.
Yoshiaki ShojiDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.ORCID 0000-0003-3074-1398
Tomohiro MurakamiDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.
Christine L BoleyDepartment of Immuno-Oncology and Clinical Research, John Wayne Cancer Institute, Santa Monica, CA 90404, USA.
Linh T TranDepartment of Genomic Sequencing Center, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.
Hunter ColeDepartment of Immuno-Oncology and Clinical Research, John Wayne Cancer Institute, Santa Monica, CA 90404, USA.
Daniel F KellyPacific Neuroscience Institute, John Wayne Cancer Institute, Saint John's Health Center, Santa Monica, CA 90404, USA.
Steven O'DayDepartment of Immuno-Oncology and Clinical Research, John Wayne Cancer Institute, Santa Monica, CA 90404, USA.
Dave S B HoonDepartment of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA 90404, USA.
Saint John's Health Center · US

Funding

ABCs Foundation NADr. Miriam and Sheldon G. Adelson Medical Research Foundation NAFashion Footwear Association of New York NAGonda Foundation NA
6 · The paper itself

Abstract

Primary cutaneous melanoma frequently metastasizes to distant organs including the brain. Identification of cell-free microRNAs (cfmiRs) found in the blood can be used as potential body fluid biomarkers for detecting and monitoring patients with melanoma brain metastasis (MBM). In this pilot study, we initially aimed to identify cfmiRs in the blood of MBM patients. Normal donors plasma (healthy,

Indexed as

bloodbrain metastasiscell-free miRNAglioblastomaimmunotherapymelanomaNGSplasmaurine

Identifiers

PMID32630542
PMCPMC7352246
OpenAlexW3037313864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.