Evidence map›Paper›PMID 32630504›Full record

ReviewLife (Basel, Switzerland)2020

Bioinformatics Analysis of Evolution and Human Disease Related Transposable Element-Derived microRNAs.

Hee-Eun Lee, Jae-Won Huh, Heui-Soo Kim

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. The Tumorigenic Role of Circular RNA-MicroRNA Axis in Cancer.International journal of molecular sciences · 2023
    Review
  5. Article
  6. An EpigeneticInternational journal of molecular sciences · 2022
    Review
  7. Integration of TE Induces Cancer Specific Alternative Splicing Events.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hee-Eun LeeNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Korea.ORCID 0000-0002-7485-9083
Jae-Won HuhNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju 28116, Korea.ORCID 0000-0001-5845-939X
Heui-Soo KimDepartment of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Korea.

Funding

National Research Foundation of Korea NRF-2018R1D1A1B07049460
6 · The paper itself

Abstract

Transposable element (TE) has the ability to insert into certain parts of the genome, and due to this event, it is possible for TEs to generate new factors and one of these factors are microRNAs (miRNA). miRNAs are non-coding RNAs made up of 19 to 24 nucleotides and numerous miRNAs are derived from TE. In this study, to support general knowledge on TE and miRNAs derived from TE, several bioinformatics tools and databases were used to analyze miRNAs derived from TE in two aspects: evolution and human disease. The distribution of TEs in diverse species presents that almost half of the genome is covered with TE in mammalians and less than a half in other vertebrates and invertebrates. Based on selected evolution-related miRNAs studies, a total of 51 miRNAs derived from TE were found and analyzed. For the human disease-related miRNAs, total of 34 miRNAs derived from TE were organized from the previous studies. In summary, abundant miRNAs derived from TE are found, however, the function of miRNAs derived from TE is not informed either. Therefore, this study provides theoretical understanding of miRNAs derived from TE by using various bioinformatics tools.

Indexed as

evolutionhuman diseasemicroRNAtransposable element derived microRNAtransposable elements

Identifiers

PMID32630504
PMCPMC7345915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.