Evidence map›Paper›PMID 32630408›Full record

ArticleInternational journal of molecular sciences2020

Distinct Local and Systemic Molecular Signatures in the Esophageal and Gastric Cancers: Possible Therapy Targets and Biomarkers for Gastric Cancer.

Iwona Bednarz-Misa, Paulina Fortuna, Dorota Diakowska, Natalia Jamrozik, Małgorzata Krzystek-Korpacka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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  14. Interleukin (IL)-7 Signaling in the Tumor Microenvironment.Advances in experimental medicine and biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Iwona Bednarz-MisaDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0001-7244-2017
Paulina FortunaDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0003-4617-798X
Dorota DiakowskaDepartment of Gastrointestinal and General Surgery, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0002-1377-5601
Natalia JamrozikDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Małgorzata Krzystek-KorpackaDepartment of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0002-2753-8092
Wroclaw Medical University · PL

Funding

Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu SUB.A040.19.016.
6 · The paper itself

Abstract

Gastric (GC) and esophageal (EC) cancers are highly lethal. Better understanding of molecular abnormalities is needed for new therapeutic targets and biomarkers to be found. Expression of 18 cancer-related genes in 31 paired normal-tumor samples was quantified by reversely-transcribed quantitative polymerase chain reaction (RTqPCR) and systemic concentration of 27 cytokines/chemokines/growth factors in 195 individuals was determined using Luminex xMAP technology. Only

Indexed as

AgedBiomarkers, TumorCell Line, TumorChemokine CCL5CytokinesEsophageal NeoplasmsFemaleGene ExpressionGene Expression ProfilingHumansInterleukin-1betaInterleukin-6MaleMiddle AgedNeoplasm Recurrence, LocalStomach NeoplasmsBiomarkers, TumorChemokine CCL5CytokinesIL1B protein, humanInterleukin-1betaInterleukin-6angiogenesiscardia cancerclaudin-2differential biomarkersepithelial-mesenchymal transitionesophageal cancerinflammationmetabolic reprogrammingtight junction proteins

Identifiers

PMID32630408
PMCPMC7349922
OpenAlexW3037825470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.