ReviewLife (Basel, Switzerland)2020
The Clinical Use of Platelet-Rich Plasma in Knee Disorders and Surgery-A Systematic Review and Meta-Analysis.
Review in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Efficacy of arthroscopic debridement combined with platelet-rich plasma injection for knee osteoarthritis: An updated systematic review and meta-analysis of randomized controlled trials.The Journal of international medical research · 2026Pooled it
- Comparison of the clinical effectiveness of activated and non-activated platelet-rich plasma in the treatment of knee osteoarthritis: a systematic review and meta-analysis.Clinical rheumatology · 2023Pooled it
- Biological augmentation of meniscal repair: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Pooled it
- Platelet-rich plasma (PRP) augmentation does not result in more favourable outcomes in arthroscopic meniscal repair: a meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022Pooled it
- Evaluation of Spin Bias in the Use of Platelet-Rich Plasma for Augmentation of Meniscal Tear Repairs.Orthopaedic journal of sports medicine · 2026Review
- Leukocyte-Rich Platelet-Rich Plasma Improves Cartilage Repair After High Tibial Osteotomy: A Second-Look Arthroscopic Study.Biomedicines · 2026Article
- Platelet-Rich Plasma in Chronic Joint Pain: An Autologous Alternative to Steroids.Current pain and headache reports · 2026Review
- Effects of Platelet-Rich Plasma Injection in Knee Osteoarthritis Stages 1-4: A Retrospective Cohort Study.Cureus · 2026Article
- Systematic reviews in PRP-augmented meniscal repair have limited methodological quality: A systematic overview.Journal of experimental orthopaedics · 2026Article
- Medial and lateral menisci vascularization level in advanced osteoarthritis of the knee.BMC musculoskeletal disorders · 2026Article
- Can PRP Enhance Hamstring Recovery Post-ACL Reconstruction? Retrospective Insights from Non-Professional Athletes.Journal of clinical medicine · 2025Article
- Spin and reporting bias in the use of platelet-rich plasma for the treatment of knee osteoarthritis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Review
- Article
- Biological Mechanisms and Clinical Challenges of Platelet-Rich Plasma in Chronic Musculoskeletal Pain: From Standardized Preparation to Multi-Omics-Guided Precision Therapy.Journal of pain research · 2025Review
- The Use of Platelet-Rich Plasma Augmentation in Meniscus Repair Results in a Lower Failure Rate than in the Control Group: A Systematic Review From Meta-analysis.Arthroscopy, sports medicine, and rehabilitation · 2024Review
- Biologic Augmentation of Isolated Meniscal Repair.Current reviews in musculoskeletal medicine · 2024Review
- Efficacy of Intraoperative Platelet-Rich Plasma After Meniscal Repair: Systematic Review and Meta-analysis.Indian journal of orthopaedics · 2024Review
- Utility of Platelet-Rich Plasma Therapy in the Management of Meniscus Injuries: A narrative review.Orthopedic reviews · 2024Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In recent years, the interest in biological treatment of knee lesions has increased, especially the application of platelet-rich plasma is of particular note. The number of articles evaluating platelet-rich plasma (PRP) efficacy in the recovery of knee disorders and during knee surgery has exponentially increased over the last decade. A systematic review with meta-analyses was performed by assessing selected studies of local PRP injections to the knee joint. The study was completed in accordance with 2009 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. A multistep search of PubMed, Embase, Cochrane Database of Systematic Reviews, and Clinicaltrials.gov was performed to identify studies on knee surgery and knee lesion treatment with PRP. Of the 4004 articles initially identified, 357 articles focusing on knee lesions were selected and, consequently, only 83 clinical trials were analyzed using the revised Cochrane risk-of-bias tool to evaluate risk. In total, seven areas of meta-analysis reported a positive effect of PRP. Among them, 10 sub-analyses demonstrated significant differences in favor of PRP when compared to the control groups (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.