ArticleJournal of clinical medicine2020
In Vivo Reflectance Confocal Microscopy-Diagnostic Criteria for Actinic Cheilitis and Squamous Cell Carcinoma of the Lip.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 23 citations in OpenAlex.
- New Insights for an Advanced Understanding of the Molecular Mechanisms in Oral Squamous Cell Carcinoma.International journal of molecular sciences · 2024Article
- Lichen Planus of the Lip-Case Series and Review of the Literature.Medicina (Kaunas, Lithuania) · 2024Observational
- Role of Cannabinoids in Oral Cancer.International journal of molecular sciences · 2024Review
- An overview of cutaneous squamous cell carcinoma imaging diagnosis methods.Frontiers in medicine · 2024Review
- Looking into the Skin in Health and Disease: From Microscopy Imaging Techniques to Molecular Analysis.International journal of molecular sciences · 2023Article
- Current Approach and Future Directions in the Diagnosis and Prognosis of Keratinocyte Carcinomas.Journal of clinical medicine · 2023Article
- Role of reflectance confocal microscopy for in vivo investigation of oral disorders: White, red and pigmented lesions.Experimental dermatology · 2023Observational
- Non-Invasive Diagnostic Techniques in Dermatology.Journal of clinical medicine · 2023Article
- Skin Cancer Pathobiology at a Glance: A Focus on Imaging Techniques and Their Potential for Improved Diagnosis and Surveillance in Clinical Cohorts.International journal of molecular sciences · 2023Review
- Review
- Recent Advances in Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2022Article
- Persistent Changes of Peripheral Blood Lymphocyte Subsets in Patients with Oral Squamous Cell Carcinoma.Healthcare (Basel, Switzerland) · 2022Article
- Artificial Intelligence-Based Approaches to Reflectance Confocal Microscopy Image Analysis in Dermatology.Journal of clinical medicine · 2022Review
- Editorial: Recent advances in keratinocyte carcinomas: From molecular mechanisms to clinical perspectives.Frontiers in medicine · 2022Article
- Actinic Cheilitis - From Risk Factors to Therapy.Frontiers in medicine · 2022Review
- Review
- Assessment of Histological Features in Squamous Cell Carcinoma Involving Head and Neck Skin and Mucosa.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Actinic cheilitis (AC) is one of the most frequent pathologies to affect the lips. Studies show that the most commonplace oral malignancy, squamous cell carcinoma (SCC), often emerges from AC lesions. Invasive diagnostic techniques performed on the lips carry a high risk of complications, but reflectance confocal microscopy (RCM), a non-invasive skin imaging technique, may change the current diagnostic pathway. This retrospective study was aimed at consolidating the RCM diagnostic criteria for AC and lip SCC. The study was conducted in two tertiary care centers in Bucharest, Romania. We included adults with histopathologically confirmed AC and SCC who also underwent RCM examination. Of the twelve lesions included in the study, four were AC and eight were SCC. An atypical honeycomb pattern and the presence of target cells in the epidermis were RCM features associated with AC. SCC was typified by the presence of complete disruption of the epidermal architecture and dermal inflammatory infiltrates. The mean blood vessel diameter in SCC was 18.55 µm larger than that in AC (
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