ArticleBrain sciences2020
Clinical Severity and Calcium Metabolism in Patients with Bipolar Disorder.
Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- The Influence of Vitamin D Intake and Status on Mental Health in Children: A Systematic Review.Nutrients · 2021Pooled it
- Vitamin D and calcium metabolism in bipolar disorder: a scoping review of contradictory evidence.International journal of bipolar disorders · 2026Review
- Does hypothalamic CCN3 hypersecretion confer postpartum mood disorder risk?Translational psychiatry · 2026Review
- Lithium: Old Drug, New tricks?Current psychiatry reports · 2025Review
- Assessment of the Correlation Between Unipolar and Bipolar Depression, Calcium Levels, Thyroid Function, and Inflammatory Markers: A Pilot Cross-Sectional Study.Psychopharmacology bulletin · 2025Article
- The impact of ADL disability in middle-aged and older adults on the incidence of hip fractures and the mediating role of depression: a longitudinal evidence from CHARLS.Frontiers in medicine · 2025Article
- Vitamin D Status in Bipolar Disorder.Nutrients · 2023Article
- Exploring the Relationship between Mood Disorders and Coexisting Health Conditions: The Focus on Nutraceuticals.Brain sciences · 2023Review
- Sleep Disturbances in Generalized Anxiety Disorder: The Role of Calcium Homeostasis Imbalance.International journal of environmental research and public health · 2023Article
- Oral calcium and vitamin D supplements differentially alter exploratory, anxiety-like behaviors and memory in male rats.PloS one · 2023Article
- The Mediation Effect of Peripheral Biomarkers of Calcium Metabolism and Chronotypes in Bipolar Disorder Psychopathology.Metabolites · 2022Article
- Vitamin D Deficiency and Risk Factors Related to Acute Psychiatric Relapses in Patients with Severe Mental Disorders: A Preliminary Study.Brain sciences · 2022Article
- Focus on Peripheral Biomarkers of Mental Disorders.Brain sciences · 2022Article
- Inflammation and Nitro-oxidative Stress as Drivers of Endocannabinoid System Aberrations in Mood Disorders and Schizophrenia.Molecular neurobiology · 2022Review
- Biological Pathways Associated with Neuroprogression in Bipolar Disorder.Brain sciences · 2021Article
- The Relationship between rs534654 Polymorphism in TMEM165 Gene and Increased Risk of Bipolar Disorder Type 1.International journal of molecular and cellular medicine · 2021Article
- Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling.Frontiers in neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parathyroid hormone (PTH), vitamin D and serum calcium play a key role in several physiological and pathological conditions. Vitamin D and PTH receptors are largely expressed in the central nervous system and are involved in the modulation of inflammatory responses. Few studies investigated the association between calcium homeostasis imbalance and psychiatric disorders. This study aims to assess calcium homeostasis imbalance in patients with bipolar disorder (BD) and its impact on clinical outcome. We recruited 199 patients with BD, who were administered with validated assessment instruments to investigate depressive, manic and anxiety symptoms, affective temperaments, childhood trauma and global functioning. Serum calcium, vitamin D and PTH levels were assessed in all patients. Levels of PTH correlated with several clinical characteristics, including the diagnosis of bipolar disorder type I (BD-I), the presence of psychotic symptoms, lithium treatment, suicidality, total number of acute episodes and of hospitalizations (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.