Evidence map›Paper›PMID 32630219›Full record

ReviewViruses2020

The Role of the Human Cytomegalovirus

Luwanika Mlera, Melissa Moy, Kristen Maness, Linh N Tran, Felicia D Goodrum

Abstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Mechanisms and Determinants of CMV Reactivation in Kidney Transplantation.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Viral and host network analysis of the human cytomegalovirus transcriptome in latency.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. A vaccine against cytomegalovirus: how close are we?The Journal of clinical investigation · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Hematopoietic stem cells and betaherpesvirus latency.Frontiers in cellular and infection microbiology · 2023
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luwanika MleraBIO5 Institute, University of Arizona, Tucson, AZ 85719, USA.
Melissa MoyGraduate Interdisciplinary Program in Cancer Biology, Tucson, AZ 85719, USA.
Kristen ManessImmunobiology Department, University of Arizona, Tucson, AZ 85719, USA.
Linh N TranImmunobiology Department, University of Arizona, Tucson, AZ 85719, USA.ORCID 0000-0003-0574-0887
Felicia D GoodrumBIO5 Institute, University of Arizona, Tucson, AZ 85719, USA.

Funding

The Administrative CoreP01AI127335 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI JAY A NELSON · 2017 to 2026
$24.6M
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsR01AI079059 · NIAID · UNIVERSITY OF ARIZONA · PI GOODRUM, FELICIA D · 2008 to 2018
$4.4M
Mechanisms of Human Cytomegalovirus Latency in Primary Human Hematopoietic CellsR37AI079059 · NIAID · UNIVERSITY OF ARIZONA · PI Felicia D Goodrum · 2019 to 2026
$3.3M
CMV Control of Host Membrane TraffickingR01AI131598 · NIAID · UNIVERSITY OF ARIZONA · PI GOODRUM, FELICIA D, WILSON, JEAN M · 2018 to 2022
$2.1M
National Institute of Allergy and Infectious Diseases AI079059National Institute of Allergy and Infectious Diseases AI127335NIAID NIH HHS R01 AI079059NIAID NIH HHS R01 AI131598NIAID NIH HHS R37 AI079059
6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) latency, the means by which the virus persists indefinitely in an infected individual, is a major frontier of current research efforts in the field. Towards developing a comprehensive understanding of HCMV latency and its reactivation from latency, viral determinants of latency and reactivation and their host interactions that govern the latent state and reactivation from latency have been identified. The polycistronic

Indexed as

Virus ActivationVirus LatencyAnimalsCytomegalovirusCytomegalovirus InfectionsHumansViral ProteinsUL135 protein, human herpesvirus 5UL136 protein, human herpesvirus 5Viral ProteinsDNA virusherpesvirusHuman cytomegaloviruslatencyreactivationUL135UL136UL138

Identifiers

PMID32630219
PMCPMC7411667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.