ArticleBrain sciences2020
Mild Cognitive Impairments Attenuate Prefrontal Cortex Activations during Walking in Older Adults.
Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07500662 (The Effect of Ankle Foot Orthosis Influences the Prefrontal Load in Stroke Patients During Dual Task Walking), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Ankle Foot Orthosis Influences the Prefrontal Load in Stroke Patients During Dual Task Walking
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Relationship between motor performance and cortical activity of older neurological disorder patients with dyskinesia using fNIRS: A systematic review.Frontiers in physiology · 2023Pooled it
- Neural Mechanisms of Motor Dysfunction in Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review.Journal of Alzheimer's disease reports · 2022Pooled it
- Can transcranial direct current stimulation combined with interactive computerized cognitive training boost cognition and gait performance in older adults with mild cognitive impairment? a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2024Trial
- Effects of different dual task training on dual task walking and responding brain activation in older adults with mild cognitive impairment.Scientific reports · 2022Trial
- Neuromuscular control mechanism during posture-cognition dual task in mild cognitive impairment: a concurrent fNIRS-sEMG-COP study.GeroScience · 2026Article
- Neuroprotective Effect of the Combined Extract ofInternational journal of molecular sciences · 2026Article
- Distributions of plantar loads are altered when walking in anxiety-inducing virtual settings but not under cognitive demand.PloS one · 2026Article
- Effects of Balance-Based Exergame Training With Variable Difficulty on Balance and Spatiotemporal Gait Outcomes in Adults With Mild Cognitive Impairment: Randomized Controlled Trial.JMIR serious games · 2025Article
- Brain Activation During Motor Preparation and Execution in Patients with Mild Cognitive Impairment: An fNIRS Study.Brain sciences · 2025Article
- Evaluation of Neural, Systemic and Extracerebral Activations During Active Walking Tasks in Older Adults Using fNIRS.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
- Gait analysis in older adults with mild cognitive impairment: a bibliometric analysis of global trends, hotspots, and emerging frontiers.Frontiers in aging · 2025Article
- Mapping the landscape of brain stimulation research: A global scientometric review on cognitive impairment.Ibrain · 2025Review
- Article
- Association of Compensatory Mechanisms in Prefrontal Cortex and Impaired Anatomical Correlates in Semantic Verbal Fluency: A Functional Near-Infrared Spectroscopy Study.Psychiatry investigation · 2024Article
- Brain activation during standing balance control in dual-task paradigm and its correlation among older adults with mild cognitive impairment: a fNIRS study.BMC geriatrics · 2024Article
- Functional Connectivity Differences in Distinct Dentato-Cortical Networks in Alzheimer's Disease and Mild Cognitive Impairment.bioRxiv : the preprint server for biology · 2024Article
- Comparison of the Influence of Dual-Task Activities on Prefrontal Activation and Gait Variables in Older Adults with Mild Cognitive Impairment during Straight and Curved Walking.Medicina (Kaunas, Lithuania) · 2024Article
- Prefrontal activity and heart rate variability during cognitive tasks may show different changes in young and older adults with and without mild cognitive impairment.Frontiers in aging neuroscience · 2024Article
- The prefrontal cortex hemodynamic responses to dual-task paradigms in older adults: A systematic review and meta-analysis.Heliyon · 2023Review
- Gait performance and prefrontal cortex activation during single and dual task walking in older adults with different cognitive levels.Frontiers in aging neuroscience · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The presence of Mild Cognitive Impairments (MCI) is associated with worse gait performance. However, the effect of MCI on cortical control of gait, as assessed during active walking, is unknown. We hypothesized that MCI would be associated with attenuated activations and limited improvement in efficiency in the Prefrontal cortex (PFC) under cognitively-demanding walking conditions. Functional Near-Infrared Spectroscopy (fNIRS) was used to assess Oxygenated Hemoglobin (HbO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.