ReviewInternational journal of molecular sciences2020
Vascular Homeostasis and Inflammation in Health and Disease-Lessons from Single Cell Technologies.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Recent advancements and limitations of intestinal organoids for clinical applications.Progress in biomedical engineering (Bristol, England) · 2026Review
- Transcriptomic characters of cochlear vascular cells with pericyte-driven angiogenetic activity.Angiogenesis · 2026Article
- Transcriptomic characters of cochlear vascular cells with pericyte-driven angiogenetic activity.Research square · 2026Article
- Article
- Rethinking Biomedical Titanium Alloy Design: A Review of Challenges from Biological and Manufacturing Perspectives.Advanced healthcare materials · 2025Review
- Inverse association between serum klotho levels and C-reactive protein levels in the US population: a cross-sectional study.BMC cardiovascular disorders · 2024Article
- Biofabrication of engineered blood vessels for biomedical applications.Science and technology of advanced materials · 2024Review
- The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity.Nature reviews. Endocrinology · 2023Review
- Cultured brain pericytes adopt an immature phenotype and require endothelial cells for expression of canonical markers and ECM genes.Frontiers in cellular neuroscience · 2023Article
- Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity.Nature metabolism · 2022Article
- The cellular landscape of the normal kidney allograft: Main players balancing the alloimmune response.Frontiers in transplantation · 2022Article
- The impact of periodontitis on vascular endothelial dysfunction.Frontiers in cellular and infection microbiology · 2022Review
- Hemodynamics Challenges for the Navigation of Medical Microbots for the Treatment of CVDs.Materials (Basel, Switzerland) · 2021Review
- Unique Angiogenesis From Cardiac Arterioles During Pericardial Adhesion Formation.Frontiers in cardiovascular medicine · 2021Article
- Delicate Role of PD-L1/PD-1 Axis in Blood Vessel Inflammatory Diseases: Current Insight and Future Significance.International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vascular system is critical infrastructure that transports oxygen and nutrients around the body, and dynamically adapts its function to an array of environmental changes. To fulfil the demands of diverse organs, each with unique functions and requirements, the vascular system displays vast regional heterogeneity as well as specialized cell types. Our understanding of the heterogeneity of vascular cells and the molecular mechanisms that regulate their function is beginning to benefit greatly from the rapid development of single cell technologies. Recent studies have started to analyze and map vascular beds in a range of organs in healthy and diseased states at single cell resolution. The current review focuses on recent biological insights on the vascular system garnered from single cell analyses. We cover the themes of vascular heterogeneity, phenotypic plasticity of vascular cells in pathologies such as atherosclerosis and cardiovascular disease, as well as the contribution of defective microvasculature to the development of neurodegenerative disorders such as Alzheimer's disease. Further adaptation of single cell technologies to study the vascular system will be pivotal in uncovering the mechanisms that drive the array of diseases underpinned by vascular dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.