Evidence map›Paper›PMID 32630091›Full record

ArticleSensors (Basel, Switzerland)2020

Assessment of Gold Bio-Functionalization for Wide-Interface Biosensing Platforms.

Lucia Sarcina, Luisa Torsi, Rosaria Anna Picca, Kyriaki Manoli, Eleonora Macchia

Abstract readLetter
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucia SarcinaDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, 70125 Bari, Italy.
Luisa TorsiDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, 70125 Bari, Italy.
Rosaria Anna PiccaDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0001-8033-098X
Kyriaki ManoliDipartimento di Chimica, Università degli Studi di Bari Aldo Moro, 70125 Bari, Italy.
Eleonora MacchiaThe Faculty of Science and Engineering, Åbo Akademi University, FI-20500 Turku, Finland.ORCID 0000-0002-1534-7336

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous improvement of the technical potential of bioelectronic devices for biosensing applications will provide clinicians with a reliable tool for biomarker quantification down to the single molecule. Eventually, physicians will be able to identify the very moment at which the illness state begins, with a terrific impact on the quality of life along with a reduction of health care expenses. However, in clinical practice, to gather enough information to formulate a diagnosis, multiple biomarkers are normally quantified from the same biological sample simultaneously. Therefore, it is critically important to translate lab-based bioelectronic devices based on electrolyte gated thin-film transistor technology into a cost-effective portable multiplexing array prototype. In this perspective, the assessment of cost-effective manufacturability represents a crucial step, with specific regard to the optimization of the bio-functionalization protocol of the transistor gate module. Hence, we have assessed, using surface plasmon resonance technique, a sustainable and reliable cost-effective process to successfully bio-functionalize a gold surface, suitable as gate electrode for wide-field bioelectronic sensors. The bio-functionalization process herein investigated allows to reduce the biorecognition element concentration to one-tenth, drastically impacting the manufacturing costs while retaining high analytical performance.

Indexed as

Biosensing TechniquesElectrodesGoldSurface Plasmon ResonanceGoldbio-functionalization optimizationbiosensorscost-effective biosensorslab-on-a-chipsurface plasmon resonance

Identifiers

PMID32630091
PMCPMC7374319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.