ArticleInternational journal of molecular sciences2020
Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in Obesity.
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04732663 (Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19), which is not on this map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Understanding Exertional Dyspnea and Exercise Intolerance in COVID-19
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Acute Sarcopenia: Systematic Review and Meta-Analysis on Its Incidence and Muscle Parameter Shifts During Hospitalisation.Journal of cachexia, sarcopenia and muscle · 2025Pooled it
- Obesity as a Risk Factor for Complications and Mortality in Individuals with SARS-CoV-2: A Systematic Review.Nutrients · 2024Pooled it
- Functional and Psychological Changes after Exercise Training in Post-COVID-19 Patients Discharged from the Hospital: A PRISMA-Compliant Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Visceral Adiposity Elevates the Risk of Critical Condition in COVID-19: A Systematic Review and Meta-Analysis.Obesity (Silver Spring, Md.) · 2021Pooled it
- Observational
- Increased fat accumulation may be associated with severe muscle wasting in critically ill patients: a prospective observational study.Scientific reports · 2025Observational
- Assessment of the Relationship between Pre-Existing Muscle Atrophy, Subcutaneous Fat Volume, and the Prognosis of COVID-19.Journal of clinical medicine · 2025Article
- Risk Factors for Long-Term Nutritional Disorders One Year After COVID-19: A Post Hoc Analysis of COVID-19 Recovery Study II.Nutrients · 2024Article
- Physical condition and perceived fatigue in post-covid patients: An observational descriptive study.Sao Paulo medical journal = Revista paulista de medicina · 2024Observational
- Assessment of body composition in adults hospitalized with acute COVID-19: a scoping review.Frontiers in nutrition · 2023Article
- Article
- Nutritional status in post SARS-Cov2 rehabilitation patients.Clinical nutrition (Edinburgh, Scotland) · 2022Observational
- Low muscle mass in COVID-19 critically-ill patients: Prognostic significance and surrogate markers for assessment.Clinical nutrition (Edinburgh, Scotland) · 2022Article
- The interplay of post-acute COVID-19 syndrome and aging: a biological, clinical and public health approach.Ageing research reviews · 2022Review
- Energy expenditure in COVID-19 mechanically ventilated patients: A comparison of three methods of energy estimation.JPEN. Journal of parenteral and enteral nutrition · 2022Article
- Post-acute COVID syndrome (long COVID): What should radiographers know and the potential impact for imaging services.Radiography (London, England : 1995) · 2022Review
- Modifications of Chest CT Body Composition Parameters at Three and Six Months after Severe COVID-19 Pneumonia: A Retrospective Cohort Study.Nutrients · 2022Article
- Article
- Overweight subjects have a higher risk of malnutrition and loss of function after severe COVID infection.Clinical nutrition ESPEN · 2022Article
- The importance of nutritional status on clinical outcomes among both ICU and Non-ICU patients with COVID-19.Clinical nutrition ESPEN · 2022Observational
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a characteristic of COVID-19 patients and the risk of malnutrition can be underestimated due to excess of fat: a paradoxical danger. Long ICU hospitalization exposes patients to a high risk of wasting and loss of lean body mass. The complex management precludes the detection of anthropometric parameters for the definition and monitoring of the nutritional status. The use of imaging diagnostics for body composition could help to recognize and treat patients at increased risk of wasting with targeted pathways. COVID-19 patients admitted to the ICU underwent computed tomography within 24 hours and about 20 days later, to evaluate the parameters of the body and liver composition. The main results were the loss of the lean mass index and a greater increase in liver attenuation in obese subjects. These could be co-caused by COVID-19, prolonged bed rest, the complex medical nutritional therapy, and the starting condition of low-grade inflammation of the obese. The assessment of nutritional status, with body composition applied to imaging diagnostics and metabolic profiles in COVID-19, will assist in prescribing appropriate medical nutritional therapy. This will reduce recovery times and complications caused by frailty.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.