Evidence map›Paper›PMID 32630017›Full record

ReviewBiomolecules2020

Mechanisms of Resistance to Immunotoxins Containing

Michael Dieffenbach, Ira Pastan

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Targeting the Inside of Cells with Biologicals: Toxin Routes in a Therapeutic Context.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  11. Article
  12. Article
  13. Synthesis of an Anti-CD7 Recombinant Immunotoxin Based on PE24 in CHO andInternational journal of molecular sciences · 2022
    Article
  14. Podocytes are lost from glomeruli before completing apoptosis.American journal of physiology. Renal physiology · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. CD3e-immunotoxin spares CD62LFrontiers in immunology · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael DieffenbachLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4264, USA.
Ira PastanLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4264, USA.
National Institutes of Health · US

Funding

Immunotoxin Therapy of Solid and Hematopoietic Tumors: Preclinical StudiesZIABC008753 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PASTAN, IRA · 2009 to 2024
$33.1M
Intramural Research Program, National Cancer Institute, National Institutes of Health ZIA BC 008753
6 · The paper itself

Abstract

Immunotoxins are a class of targeted cancer therapeutics in which a toxin such as

Indexed as

Drug Resistance, NeoplasmADP Ribose TransferasesBacterial ToxinsCell SurvivalClinical Trials as TopicCytosolExotoxinsHumansImmunotoxinsNeoplasmsPeptide Elongation Factor 2Protein TransportPseudomonas aeruginosa Exotoxin AVirulence FactorsADP Ribose TransferasesBacterial ToxinsExotoxinsImmunotoxinsPeptide Elongation Factor 2Pseudomonas aeruginosa Exotoxin AVirulence Factorscombination therapyimmunotoxinimmunotoxin resistancePseudomonas exotoxin A

Identifiers

PMID32630017
PMCPMC7408526
OpenAlexW3040005174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.