Evidence map›Paper›PMID 32629978›Full record

ArticleNutrients2020

Obesity, Insulin Resistance, and Hyperandrogenism Mediate the Link between Poor Diet Quality and Ovarian Dysmorphology in Reproductive-Aged Women.

Maryam Kazemi, Brittany Y Jarrett, Heidi Vanden Brink, Annie W Lin, Kathleen M Hoeger, Steven D Spandorfer, Marla E Lujan

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  11. Associations between dietary patterns and parameters of ovarian reserve in Polish women of reproductive age.International journal of occupational medicine and environmental health · 2024
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  15. Reduction in the Free Androgen Index in Overweight Women After Sixty Days of a Low Glycemic Diet.Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Maryam KazemiDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-6001-7208
Brittany Y JarrettDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.
Heidi Vanden BrinkDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.
Annie W LinDepartment of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Evanston, IL 60611, USA.ORCID 0000-0002-0045-8826
Kathleen M HoegerDepartment of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY 14623, USA.
Steven D SpandorferPerelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Marla E LujanDepartment of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Evanston, IL 60611, USA.ORCID 0000-0002-7203-5814
Cornell University · USNorthwestern University · USUniversity of Rochester Medical Center · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Cancer Prevention, Control, and Survivorship Research Training ProgramT32CA193193 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian L Hitsman, BETINA YANEZ · 2015 to 2026
$3.8M
Academy of Nutrition and Dietetics Foundation N/ACIHR 146182Division of Nutritional Sciences at Cornell University N/ANational Institutes of Health fellowship awards T32-DK007158 and T32-CA193193NCATS NIH HHS UL1 TR002384NCI NIH HHS T32 CA193193NIH HHS R56-HD089962 and ULTR000457
6 · The paper itself

Abstract

The relationship between diet quality and ovarian morphology has biological plausibility yet remains unclear and was therefore evaluated. In a multicenter cross-sectional analysis, four dietary patterns were scored for 111 consecutive reproductive-aged women (18-45 years) using (1) Healthy Eating Index (HEI-2015); (2) alternative HEI-2010; (3) alternate Mediterranean Diet (aMED); (4) and Dietary Approaches to Stop Hypertension (DASH) indices. Ovarian volume (OV) and follicle number per ovary (FNPO) were evaluated on transvaginal ultrasonography. Relationships between dietary and ovarian morphology indices were evaluated by linear regression and mediation analyses. Associations between aMED and DASH scores and OV/FNPO were completely mediated by obesity, insulin resistance, and hyperandrogenism (All:

Indexed as

Insulin ResistanceAdolescentAdultClinical Trials as TopicCross-Sectional StudiesDietDietary Approaches To Stop HypertensionDiet, HealthyDiet, MediterraneanFemaleHumansHyperandrogenismLinear ModelsMediation AnalysisMiddle AgedObesityDietary Approaches to Stop HypertensionfertilityMediterranean Dietmetabolismovary

Identifiers

PMID32629978
PMCPMC7399845
OpenAlexW3038619279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.