ArticleMarine drugs2020
Laminarin Attenuates Ultraviolet-Induced Skin Damage by Reducing Superoxide Anion Levels and Increasing Endogenous Antioxidants in the Dorsal Skin of Mice.
Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 49 citations in OpenAlex.
- Plant-Derived Natural Products: An In-depth Review of Compounds and Potential Applications in Skin Aging.Chinese journal of integrative medicine · 2026Review
- Laminarin attenuates irradiation-induced salivary gland hypofunction in mice: association with enhanced Nrf2-associated antioxidant responses.Odontology · 2026Article
- Algae-Derived Bioactive Compounds as Platforms for Translational Biotechnology and Health Applications.Biotech (Basel (Switzerland)) · 2026Review
- Mediterranean Seaweed Polysaccharides: Insight into Chemical Structures, Applications, and Structure/Application Correlations.Marine drugs · 2025Review
- Pro-Angiogenic and Wound-Healing Potential of Bioactive Polysaccharides Extracted from Moroccan AlgaeLife (Basel, Switzerland) · 2025Article
- Marine Macroalgae in Topical Formulations: Bioactive Compounds, Variability, Analytical Challenges and Skin Benefits.Pharmaceutics · 2025Review
- Antioxidant and Anti-Inflammatory Effects of CrudeAntioxidants (Basel, Switzerland) · 2025Article
- Advancements in the Extraction, Characterization, and Bioactive Potential of Laminaran: A Review.Foods (Basel, Switzerland) · 2025Review
- Epigallocatechin Gallate inPharmaceuticals (Basel, Switzerland) · 2025Article
- Review
- From algae to advancements: laminarin in biomedicine.RSC advances · 2024Review
- Rehashing Our Insight of Seaweeds as a Potential Source of Foods, Nutraceuticals, and Pharmaceuticals.Foods (Basel, Switzerland) · 2023Review
- Ethyl Acetate Extract of Marine Algae,Marine drugs · 2022Article
- Enzyme-Treated Caviar Prevents UVB Irradiation-Induced Skin Photoaging.Marine drugs · 2022Article
- Protective Effects of Topical Administration of Laminarin in Oxazolone-Induced Atopic Dermatitis-like Skin Lesions.Marine drugs · 2022Article
- Natural Compounds and Products from an Anti-Aging Perspective.Molecules (Basel, Switzerland) · 2022Review
- Protective Effects of Orange Sweet Pepper Juices Prepared by High-Speed Blender and Low-Speed Masticating Juicer against UVB-induced Skin Damage in SKH-1 Hairless Mice.Molecules (Basel, Switzerland) · 2022Article
- Area light source-triggered latent angiogenic molecular mechanisms intensify therapeutic efficacy of adult stem cells.Bioengineering & translational medicine · 2022Article
- Biomaterials from the sea: Future building blocks for biomedical applications.Bioactive materials · 2021Review
- Echinochrome A Protects against Ultraviolet B-induced Photoaging by Lowering Collagen Degradation and Inflammatory Cell Infiltration in Hairless Mice.Marine drugs · 2021Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 1 country.
Funding
Abstract
A number of studies have demonstrated that marine carbohydrates display anti-oxidant, anti-melanogenic, and anti-aging activities in the skin. Laminarin (LA), a low-molecular-weight polysaccharide, is found in brown algae. The benefits of LA in ultraviolet B (UVB) induced photodamage of the skin have not been reported. The aim of this study was to investigate the effects of pre-treated LA on histopathological changes and oxidative damage in mouse dorsal skin on day 5, following repeated UVB exposure. Histopathology, Western blot analysis and immunohistochemical studies showed that epidermal thickness in the UVB group was significantly increased; however, the thickness in the UVB group treated with LA (LA/UVB group) was less compared with that of the UVB group. Collagen fibers in the dermis of the UVB group were significantly decreased and destroyed, whereas, in the LA/UVB group, the density of collagen fibers was significantly increased compared with that of the UVB group. Oxidative stress due to superoxide anion production measured via dihydroethidium fluorescence staining was dramatically increased in the UVB group, whereas in the LA/UVB group, the oxidative stress was significantly decreased. Expressions of SOD1, glutathione peroxidase and catalase were markedly reduced in the UVB group, whereas in the LA/UVB group, they were significantly higher along with SOD2 than in the control group. Taken together, our results indicate that LA pretreatment prevents or attenuates skin damage, by decreasing oxidative stress and increasing antioxidant enzymes in mouse dorsal skin.
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