Evidence map›Paper›PMID 32629783›Full record

ReviewNutrients2020

Neuroimaging of Sex/Gender Differences in Obesity: A Review of Structure, Function, and Neurotransmission.

Danielle S Kroll, Dana E Feldman, Catherine L Biesecker, Katherine L McPherson, Peter Manza, Paule Valery Joseph, Nora D Volkow, Gene-Jack Wang

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  3. Trial
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  5. Article
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  7. Article
  8. PET-MRI Applications and Future Prospects in Psychiatry.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  9. Article
  10. Article
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  12. Article
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  17. Article
  18. Article
  19. Clinical and Therapeutic Implications of Male Obesity.Journal of clinical medicine · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Danielle S KrollLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.ORCID 0000-0002-9624-504X
Dana E FeldmanLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.
Catherine L BieseckerLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.
Katherine L McPhersonLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.
Peter ManzaLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.
Paule Valery JosephLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.ORCID 0000-0002-1198-9622
Nora D VolkowLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.
Gene-Jack WangLaboratory of Neuroimaging, National Institute of Alcohol Abuse and Alcoholism, Bethesda, MD 20814, USA.
National Institute on Alcohol Abuse and Alcoholism · USNational Institute of Nursing Research · USNational Institute on Drug Abuse · US

Funding

Neurobiology of Substance Abuse and AddictionZIAAA000550 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI VOLKOW, NORA D. · 2009 to 2025
$115.1M
Sensory Science and Metabolism; Molecular and Neuronal MechanismsZIANR000035 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI JOSEPH, PAULE · 2018 to 2020
$1.7M
NIAAA NIH HHS Y1AA-3009
6 · The paper itself

Abstract

While the global prevalence of obesity has risen among both men and women over the past 40 years, obesity has consistently been more prevalent among women relative to men. Neuroimaging studies have highlighted several potential mechanisms underlying an individual's propensity to become obese, including sex/gender differences. Obesity has been associated with structural, functional, and chemical alterations throughout the brain. Whereas changes in somatosensory regions appear to be associated with obesity in men, reward regions appear to have greater involvement in obesity among women than men. Sex/gender differences have also been observed in the neural response to taste among people with obesity. A more thorough understanding of these neural and behavioral differences will allow for more tailored interventions, including diet suggestions, for the prevention and treatment of obesity.

Indexed as

Sex FactorsAdultBrainBrain MappingFemaleHumansMaleNeuroimagingObesitySynaptic TransmissionTaste PerceptiondopaminegenderMRIneuroimagingobesityopioidPETserotoninsextaste

Identifiers

PMID32629783
PMCPMC7400469
OpenAlexW3038126887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.