Evidence map›Paper›PMID 32629779›Full record

ReviewMicromachines2020

Novel Strategies in Artificial Organ Development: What Is the Future of Medicine?

Marta Klak, Tomasz Bryniarski, Patrycja Kowalska, Magdalena Gomolka, Grzegorz Tymicki, Katarzyna Kosowska, Piotr Cywoniuk, Tomasz Dobrzanski, Pawel Turowski, Michal Wszola

Open access · goldAbstract readReview
In one paragraph

Review in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. 3D Printing of Physical Organ Models: Recent Developments and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marta KlakFoundation of Research and Science Development, 01-793 Warsaw, Poland.ORCID 0000-0003-3901-586X
Tomasz BryniarskiFoundation of Research and Science Development, 01-793 Warsaw, Poland.
Patrycja KowalskaFoundation of Research and Science Development, 01-793 Warsaw, Poland.ORCID 0000-0003-0635-7214
Magdalena GomolkaFoundation of Research and Science Development, 01-793 Warsaw, Poland.ORCID 0000-0002-7067-5252
Grzegorz TymickiFoundation of Research and Science Development, 01-793 Warsaw, Poland.
Katarzyna KosowskaFoundation of Research and Science Development, 01-793 Warsaw, Poland.
Piotr CywoniukFoundation of Research and Science Development, 01-793 Warsaw, Poland.
Tomasz DobrzanskiFoundation of Research and Science Development, 01-793 Warsaw, Poland.
Pawel TurowskiFoundation of Research and Science Development, 01-793 Warsaw, Poland.
Michal WszolaFoundation of Research and Science Development, 01-793 Warsaw, Poland.

Funding

Narodowe Centrum Badań i Rozwoju STRATEGMED3/305813/2/NCBR/2017
6 · The paper itself

Abstract

The technology of tissue engineering is a rapidly evolving interdisciplinary field of science that elevates cell-based research from 2D cultures through organoids to whole bionic organs. 3D bioprinting and organ-on-a-chip approaches through generation of three-dimensional cultures at different scales, applied separately or combined, are widely used in basic studies, drug screening and regenerative medicine. They enable analyses of tissue-like conditions that yield much more reliable results than monolayer cell cultures. Annually, millions of animals worldwide are used for preclinical research. Therefore, the rapid assessment of drug efficacy and toxicity in the early stages of preclinical testing can significantly reduce the number of animals, bringing great ethical and financial benefits. In this review, we describe 3D bioprinting techniques and first examples of printed bionic organs. We also present the possibilities of microfluidic systems, based on the latest reports. We demonstrate the pros and cons of both technologies and indicate their use in the future of medicine.

Indexed as

3D bioprintingbioinkbionic tissuecell cultureorgan-on-a-chip

Identifiers

PMID32629779
PMCPMC7408042
OpenAlexW3037588360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.