Evidence map›Paper›PMID 32628540›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Aldosterone-dependent and -independent regulation of Na

Lei Yang, Gustavo Frindt, Yuanyuan Xu, Shinichi Uchida, Lawrence G Palmer

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. ENaC processing in rat kidney: effects of salt loading and ADH.American journal of physiology. Renal physiology · 2026
    Article
  3. Article
  4. How Does Dietary Potassium Influence BP?Journal of the American Society of Nephrology : JASN · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Aldosterone-independent regulation of K + secretion in the distal nephron.Current opinion in nephrology and hypertension · 2024
    Review
  9. Influence of proteolytic cleavage of ENaC's γ subunit upon NaAmerican journal of physiology. Renal physiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Directing two-way traffic in the kidney: A tale of two ions.The Journal of general physiology · 2022
    Article
  15. Expression of ENaC subunits in epithelia.The Journal of general physiology · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Lei YangDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Gustavo FrindtDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Yuanyuan XuDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Shinichi UchidaDepartment of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Lawrence G PalmerDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Cornell University · USHarbin Medical University · CNTokyo Medical and Dental University · JP

Funding

Regulation of ENaC Trafficking and Activity in the KidneyR01DK111380 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI PALMER, LAWRENCE G · 2017 to 2025
$3.1M
Control of Renal Na and K ExcretionR01DK099284 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI PALMER, LAWRENCE G, WANG, TONG WANG · 2014 to 2017
$2.3M
Defective flow-dependent tubule transport in the pathogenesis of kidney diseaseR01DK117650 · NIDDK · YALE UNIVERSITY · PI WANG, TONG WANG · 2019 to 2022
$1.5M
HHS | National Institutes of Health (NIH) 1R01-DK099284HHS | National Institutes of Health (NIH) 1R01-DK111380NIDDK NIH HHS R01 DK099284NIDDK NIH HHS R01 DK111380NIDDK NIH HHS R01 DK117650
6 · The paper itself

Abstract

We investigated the regulation of Na

Indexed as

AnimalsCytochrome P-450 CYP11B2Epithelial Sodium ChannelsKidney Tubules, CollectingMiceNatriuresisPotassiumSodiumSodium, DietaryCytochrome P-450 CYP11B2Epithelial Sodium ChannelsPotassiumSodiumSodium, Dietaryaldosterone synthaseamiloride-sensitive currentbenzamilhigh-K+ dietlow-Na+ diet

Identifiers

PMID32628540
PMCPMC7473898
OpenAlexW3038699076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.