Evidence map›Paper›PMID 32628466›Full record

ArticleInorganic chemistry2020

Amino-Functionalized Mesoporous Silica Nanoparticle-Encapsulated Octahedral Organoruthenium Complex as an Efficient Platform for Combatting Cancer.

Marina Martínez-Carmona, Quy P Ho, Jérémy Morand, Ana García, Enrique Ortega, Luiza C S Erthal, Eduardo Ruiz-Hernandez, M Dolores Santana, José Ruiz, Maria Vallet-Regí and 1 more

Open access · greenAbstract read
In one paragraph

Article in Inorganic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Platinum Group Metals against Parasites: State of the Art and Future Perspectives.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Marina Martínez-CarmonaSchool of Chemistry and CRANN, Trinity College, The University of Dublin (TCD), Dublin 2, Ireland.ORCID http://orcid.org/0000-0002-2026-6266
Quy P HoSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin (TCD), Dublin 2, Ireland.
Jérémy MorandSchool of Chemistry and CRANN, Trinity College, The University of Dublin (TCD), Dublin 2, Ireland.
Ana GarcíaDepartment of Chemistry in Pharmaceutical Sciences, School of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, 28040 Madrid, Spain.
Enrique OrtegaDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.
Luiza C S ErthalSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin (TCD), Dublin 2, Ireland.
Eduardo Ruiz-HernandezSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin (TCD), Dublin 2, Ireland.
M Dolores SantanaDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.ORCID http://orcid.org/0000-0002-1446-8232
José RuizDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.ORCID http://orcid.org/0000-0002-0834-337X
Maria Vallet-RegíDepartment of Chemistry in Pharmaceutical Sciences, School of Pharmacy, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, 28040 Madrid, Spain.
Yurii K Gun'koSchool of Chemistry and CRANN, Trinity College, The University of Dublin (TCD), Dublin 2, Ireland.ORCID http://orcid.org/0000-0002-4772-778X
Trinity College Dublin · IEUniversidad de Murcia · ESUniversidad Complutense de Madrid · ES

Funding

Wellcome Trust
6 · The paper itself

Abstract

In the process of synthesis of a new drug, as important as the drug itself is the formulation used, because the same compound can present a very different efficacy depending on how it is administered. In this work, we demonstrate how the antitumor capacity of a new octahedral organoruthenium complex, [Ru(ppy-CHO)(phen)

Indexed as

Antineoplastic AgentsApoptosisCell Line, TumorCoordination ComplexesDrug CarriersDrug Screening Assays, AntitumorHumansNanoparticlesRutheniumSilicon DioxideAntineoplastic AgentsCoordination ComplexesDrug CarriersRutheniumSilicon Dioxide

Identifiers

PMID32628466
PMCPMC7116277
OpenAlexW3038310697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.