ArticleThe British journal of radiology2020
Biomarkers of pituitary macroadenomas aggressive behaviour: a conventional MRI and DWI 3T study.
Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- [Frontiers in endocrinology · 2026Article
- Radiological Differentiation of Pituitary Adenomas From Other Sellar Masses: A Systematic Review.Cureus · 2025Review
- Concomitant Prediction of the Ki67 and PIT-1 Expression in Pituitary Adenoma Using Different Radiomics Models.Journal of imaging informatics in medicine · 2025Article
- Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas.Pituitary · 2024Article
- MRI and Trouillas' grading system of pituitary tumors: the usefulness of T2 signal intensity volumetric values.Neuroradiology · 2023Article
- Whole-tumor histogram analysis of multi-parametric MRI for differentiating brain metastases histological subtypes in lung cancers: relationship with the Ki-67 proliferation index.Neurosurgical review · 2023Article
- Refractory somatotroph adenomas.Pituitary · 2023Review
- Shape and texture analyses based on conventional MRI for the preoperative prediction of the aggressiveness of pituitary adenomas.European radiology · 2023Article
- Prediction of Higher Ki-67 Index in Pituitary Adenomas by Pre- and Intra-Operative Clinical Characteristics.Brain sciences · 2022Article
- Apparent Diffusion Coefficient Histogram Analysis for the Preoperative Evaluation of Ki-67 Expression in Pituitary Macroadenoma.Clinical neuroradiology · 2022Article
- A Nomogram for Preoperatively Predicting the Ki-67 Index of a Pituitary Tumor: A Retrospective Cohort Study.Frontiers in oncology · 2021Article
- Prediction of the Recurrence of Non-Functioning Pituitary Adenomas Using Preoperative Supra-Intra Sellar Volume and Tumor-Carotid Distance.Frontiers in endocrinology · 2021Article
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Authors and funding
9 authors.
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Abstract
objectivePituitary macroadenomas (PAs) are usually defined as benign intracranial tumors. However, they may present local aggressive course. High Ki67 labelling index (LI) values have been related to an aggressive tumor behavior. A recent clinicopathological classification of PA based on local invasiveness and proliferation indexes, divided them in groups with different prognosis. We evaluated the utility of conventional MRI (cMRI) and diffusion-weighted imaging (DWI), in predicting the Ki67- LI according the clinicopathological classification.
methods17 patients (12 M and 5 F) who underwent surgical removal of a PA were studied. cMRI features, quantification of
resultsNegative correlations were observed between Ki-67 LI, ADCm (ρ = - 0.67,
conclusionAdding quantitative measures of ADC values to cMRI could be used routinely as a non-invasive marker of specific predictive biomarker of the proliferative activity of PA. ADVANCES IN KNOWLEDGE: Routinely use of DWI on diagnostic work-up of pituitary adenomas may help in establish the likely biological aggressive lesions.
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