ArticleJournal of diabetes investigation2021
Sex differences in sarcopenia and frailty among community-dwelling Korean older adults with diabetes: The Korean Frailty and Aging Cohort Study.
Article in Journal of diabetes investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04717869 (Identifying Modifiable PAtient Centered Therapeutics Frailty), which is not on this map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identifying Modifiable PAtient Centered Therapeutics Frailty: An Observational Cohort Study
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effects of functional task training on physical performance in older adults: a systematic review and meta-analysis.European geriatric medicine · 2026Pooled it
- The current state and development trends of frailty research in diabetic patients: a bibliometric analysis.Frontiers in medicine · 2025Pooled it
- Prevalence and risk factors of frailty in older adults with diabetes: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Prevalence of Sarcopenia and Its Association With Diabetes: A Meta-Analysis of Community-Dwelling Asian Population.Frontiers in medicine · 2021Pooled it
- Metabolic-inflammatory axis linking diabetes and sarcopenia: cross-population evidence and explainable ai-based risk modeling.Acta diabetologica · 2026Article
- Frailty in older adults with type 2 diabetes: the importance of metabolic control and treatment adherence.BMC geriatrics · 2026Article
- Sex-specific associations between type 2 diabetes and muscle health in middle-aged adults.Diabetology & metabolic syndrome · 2025Article
- Frailty Detection in Older Adults with Diabetes: A Scoping Review of Assessment Tools and Their Link to Key Clinical Outcomes.Journal of clinical medicine · 2024Article
- Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort.BMC geriatrics · 2024Article
- The bidirectional relationship between sarcopenia and disability in China: a longitudinal study from CHARLS.Frontiers in public health · 2024Article
- Cross-sectional comparison of the association between three different insulin resistance surrogates and frailty: NHANES 1999-2018.Frontiers in endocrinology · 2024Article
- Musculoskeletal complications in patients with diabetes mellitus.The Korean journal of internal medicine · 2022Review
- Sex differences in frailty of geriatric outpatients with type 2 diabetes mellitus: a multicentre cross-sectional study.Scientific reports · 2022Article
- Prospective association between dietary magnesium intake and physical performance in older women and men.European journal of nutrition · 2022Article
- Gender differences in risk factors for the 2 year development of sarcopenia in community-dwelling older adults.Journal of cachexia, sarcopenia and muscle · 2022Article
- Sarcopenia in elderly diabetes.Journal of diabetes investigation · 2022Article
- A study on the prevalence and related factors of frailty and pre-frailty in the older population with diabetes in China: A national cross-sectional study.Frontiers in public health · 2022Article
- Muscle strength, an independent determinant of glycemic control in older adults with long-standing type 2 diabetes: a prospective cohort study.BMC geriatrics · 2021Article
- The prevalence and risk factors of sarcopenia in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2021Article
- Sex differences in sarcopenia and frailty among community-dwelling Korean older adults with diabetes: The Korean Frailty and Aging Cohort Study.Journal of diabetes investigation · 2021Article
Corrections and comments
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Authors and funding
11 authors at 9 institutions in 1 country.
Funding
Abstract
AIMS/
introductionWe aimed to examine the prevalence of sarcopenia and frailty in Korean older adults with diabetes compared with individuals without diabetes. MATERIALS AND
methodsWe analyzed the data of 2,403 participants aged 70-84 years enrolled in the Korean Frailty and Aging Cohort Study. Sarcopenia was defined using the Asian Working Group for Sarcopenia and the Foundation for the National Institutes of Health. Frailty was assessed by the Cardiovascular Health Study frailty phenotype criteria.
resultsThe mean age of the participants was 76.0 ± 3.9 years, and 47.2% were men. The prevalence of diabetes was 30.2% in men and 25.8% in women. Adults with diabetes showed a lower muscle mass index (appendicular skeletal muscle mass/body mass index) and handgrip strength in both sexes, but only the women showed decreased physical performance. Women with diabetes presented a higher prevalence of sarcopenia diagnosed by the Foundation for the National Institutes of Health criteria, and frailty compared with participants without diabetes (sarcopenia 14.7% vs 8.5%, P = 0.001; frailty 9.5% vs 4.9%, P = 0.003). Men in the high and middle tertiles for homeostatic model assessment of insulin resistance presented a significantly higher prevalence of sarcopenia, compared with men in the low tertile homeostatic model assessment of insulin resistance (high tertile 16.6%, middle tertile 13.3%, low tertile 8.6%).
conclusionsIn older adults with diabetes, muscle mass index and muscle strength were lower than in those without diabetes. However, the prevalence of sarcopenia and frailty was higher and physical performance was lower only in women with diabetes.
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