Evidence map›Paper›PMID 32627182›Full record

ArticleEuropean journal of immunology2020

Induction of diverse T cell memory through antibody-mediated activation in mice.

Matthew D Taylor, Mariana R Brewer, Clifford S Deutschman

Open access · bronzeAbstract readLetter
In one paragraph

Article in European journal of immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. IL17FMolecular medicine (Cambridge, Mass.) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew D TaylorThe Division of Critical Care Medicine, Department of Pediatrics, Cohen Children's Medical Center/Northwell Health, New Hyde Park, NY and the Sepsis Research Laboratory, the Feinstein Institute for Medical Research, Manhasset, NY, USA.ORCID 0000-0003-2643-3050
Mariana R BrewerThe Division of Critical Care Medicine, Department of Pediatrics, Cohen Children's Medical Center/Northwell Health, New Hyde Park, NY and the Sepsis Research Laboratory, the Feinstein Institute for Medical Research, Manhasset, NY, USA.
Clifford S DeutschmanThe Division of Critical Care Medicine, Department of Pediatrics, Cohen Children's Medical Center/Northwell Health, New Hyde Park, NY and the Sepsis Research Laboratory, the Feinstein Institute for Medical Research, Manhasset, NY, USA.
Northwell Health · US

Funding

Orexinergic Modulation of Experimental SepsisR01GM121102 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DEUTSCHMAN, CLIFFORD SCOTT, PAVLOV, VALENTIN ATANASSOV · 2017 to 2020
$1.6M
Effects of Memory T Cells on the Response to Cecal Ligation and PunctureK08GM132794 · NIGMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI TAYLOR, MATTHEW DAVID · 2019 to 2022
$782k
NIGMS NIH HHS K08 GM132794NIGMS NIH HHS R01 GM121102Thrasher Research Fund 14734
6 · The paper itself

Abstract

Recent studies have demonstrated that laboratory mice lack a robust repertoire of memory T cell. Administration of an anti-CD3ε activating antibody (clone 145-2C11) induces persistent CD4 and CD8 T cell memory in both lymphatic and solid organs while maintaining T cell responses and without increased anergy or altering innate immunity.

Indexed as

AnimalsAntibodies, MonoclonalCD3 ComplexCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesClonal AnergyImmunologic MemoryLymphocyte ActivationMiceMice, Inbred C57BLAntibodies, MonoclonalCD3 Complexanti-CD3ε antibodyCD4 T cellsCD 8 T cellsT cell activationT cell memory formation

Identifiers

PMID32627182
PMCPMC8019190
OpenAlexW3040553801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.