Evidence map›Paper›PMID 32626783›Full record

ReviewJournal of diabetes research2020

Genetic and Biological Effects of ICAM-1 E469K Polymorphism in Diabetic Kidney Disease.

Xiuli Zhang, Norhashimah Abu Seman, Henrik Falhammar, Kerstin Brismar, Harvest F Gu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of diabetes research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Xiuli ZhangDepartment of Nephrology, The second People's Hospital, Shenzhen, The first Affiliated Hospital of Shenzhen University, Guangdong 518000, China.ORCID https://orcid.org/0000-0001-8123-8288
Norhashimah Abu SemanCardiovascular, Diabetes and Nutrition Research Center, Institute for Medical Research, Kuala Lumpur 50588, Malaysia.
Henrik FalhammarRolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.ORCID https://orcid.org/0000-0002-5622-6987
Kerstin BrismarRolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.
Harvest F GuCenter for Pathophysiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.ORCID https://orcid.org/0000-0003-4578-5449
China Pharmaceutical University · CNInstitute for Medical Research · MYKarolinska Institutet · SEKarolinska University Hospital · SEShenzhen Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic kidney disease (DKD) is a complex disease, in which local inflammatory stress results from both metabolic and hemodynamic derangements. Intercellular adhesion molecule 1 (ICAM-1) is an acute-phase protein marker of inflammation. In the recent years, clinical observations have reported that increased serum/plasma ICAM-1 levels are positively correlated with albuminuria in the patients with type 1 (T1D) and type 2 diabetes (T2D). Genetic association studies have demonstrated that genetic polymorphisms, including SNP rs5498 (E469K, G/A), in the

Indexed as

Diabetic NephropathiesHumansIntercellular Adhesion Molecule-1Polymorphism, Single NucleotideICAM1 protein, humanIntercellular Adhesion Molecule-1

Identifiers

PMID32626783
PMCPMC7313107
OpenAlexW3035409338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.