Evidence map›Paper›PMID 32626759›Full record

ArticleBioMed research international2020

Profiling and Bioinformatics Analysis of Differentially Expressed circRNAs in Spinal Ligament Tissues of Patients with Ankylosing Spondylitis.

Jianqiang Kou, Guoming Liu, Xiangyun Liu, Tianmi Li, Ying Wei, Yuanliang Sun, Ting Wang, Yingzhen Wang, Xiujun Zheng

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jianqiang KouDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Guoming LiuDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Xiangyun LiuDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Tianmi LiDepartment of Operating Room, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Ying WeiDepartment of Operating Room, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Yuanliang SunDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Ting WangDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Yingzhen WangDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.
Xiujun ZhengDepartment of Orthopedics, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.ORCID https://orcid.org/0000-0003-2485-3430
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have reported that circular RNAs (circRNAs) play a crucial regulatory role in a variety of human diseases. However, the roles of circRNAs in ankylosing spondylitis (AS) remain unclear. In this study, we conducted circRNA expression profiling of the spinal ligament tissues of patients with AS by RNA sequencing (RNA-seq) and analyzed the potential functions of differentially expressed circRNA by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses to investigate the potential mechanisms associated with AS. The results showed that a total of 1,172 circRNAs were detected in the spinal ligament tissue samples, of which 123 circRNAs were significantly differentially expressed by a fold change ≥ 1.5 and

Indexed as

AgedComputational BiologyFemaleGene Expression ProfilingHumansLigaments, ArticularMaleMiddle AgedRNA, CircularSpineSpondylitis, AnkylosingTranscriptomeRNA, Circular

Identifiers

PMID32626759
PMCPMC7313148
OpenAlexW3034741913

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.