Evidence map›Paper›PMID 32626742›Full record

ArticleBioMed research international2020

Chitosan-Based Delivery of Avian Reovirus Fusogenic Protein p10 Gene:

Claudia Robles-Planells, Carlos Barrera-Avalos, Leonel E Rojo, Eugenio Spencer, Marcelo Cortez-San Martin, Silvia Matiacevich, Jorge Pavez, Luis A Milla, Franco D Navarro, Brandon A Martínez and 6 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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  6. BioMed research international · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Claudia Robles-PlanellsDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.ORCID https://orcid.org/0000-0003-3339-8871
Carlos Barrera-AvalosDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.ORCID https://orcid.org/0000-0001-6160-9563
Leonel E RojoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.ORCID https://orcid.org/0000-0002-0188-2266
Eugenio SpencerDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Marcelo Cortez-San MartinDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Silvia MatiacevichCentro de Tecnología de los Alimentos, Facultad Tecnológica, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.ORCID https://orcid.org/0000-0003-3797-6034
Jorge PavezDepartamento de Química de los Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Luis A MillaCentro de Investigación Biomédica y Aplicada (CIBAP), Escuela de Medicina, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Chile.ORCID https://orcid.org/0000-0001-9738-6234
Franco D NavarroDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Brandon A MartínezDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Francisco J BravoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Andrea MellaDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Juan Pablo Huidobro-ToroDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.
Ricardo FernandezDepartamento de Salud, Universidad de Los Lagos, Osorno, Chile.
Alejandro EscobarLaboratorio Biología Celular y Molecular, Instituto de Investigación en Ciencias Odontológicas, Facultad de Odontología, Universidad de Chile, Santiago, Chile.ORCID https://orcid.org/0000-0002-1587-4179
Claudio Acuña CastilloDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, USACH, Alameda, 3363 Santiago, Chile.ORCID https://orcid.org/0000-0003-3607-6077
Universidad de Santiago de Chile · CLUniversidad de Los Lagos · CLUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune responses. A feasible explanation for the oncolytic effects and immune system activation is through the expression of the fusogenic reovirus protein. In this work, we evaluated the

Indexed as

Cancer VaccinesMelanoma, ExperimentalOrthoreovirus, AvianRecombinant Fusion ProteinsViral ProteinsAnimalsAntineoplastic AgentsCell SurvivalChitosanDrug Delivery SystemsMiceMice, Inbred C57BLNanoparticlesTransfectionAntineoplastic AgentsCancer VaccinesChitosanRecombinant Fusion ProteinsViral Proteins

Identifiers

PMID32626742
PMCPMC7306838
OpenAlexW3034273237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.