Evidence map›Paper›PMID 32626700›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Cell Membrane-Based Biomimetic Nanoparticles and the Immune System: Immunomodulatory Interactions to Therapeutic Applications.

Manuela Sushnitha, Michael Evangelopoulos, Ennio Tasciotti, Francesca Taraballi

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

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  10. Target, silence, replace: a review on RNA-based drugs in modern medicine.Frontiers in cell and developmental biology · 2026
    Review
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  14. Nanomedicine Innovations for Lung Cancer Diagnosis and Therapy.ACS applied materials & interfaces · 2025
    Review
  15. Article
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  19. Cerebral Aneurysm: Filling the Gap Between Pathophysiology and Nanocarriers.International journal of molecular sciences · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manuela SushnithaDepartment of Bioengineering, Rice University, Houston, TX, United States.
Michael EvangelopoulosCenter for Musculoskeletal Regeneration, Houston Methodist Research Institute, Houston, TX, United States.
Ennio TasciottiCenter for Musculoskeletal Regeneration, Houston Methodist Research Institute, Houston, TX, United States.
Francesca TaraballiCenter for Musculoskeletal Regeneration, Houston Methodist Research Institute, Houston, TX, United States.

Funding

Targeting the JAK/STAT3 Pathway in Triple-Negative Breast Cancer Using Biomimetic NanoparticlesF31CA232705 · NCI · RICE UNIVERSITY · PI SUSHNITHA, MANUELA · 2018 to 2020
$121k
NCI NIH HHS F31 CA232705
6 · The paper itself

Abstract

Nanoparticle-based drug delivery systems have been synthesized from a wide array of materials. The therapeutic success of these platforms hinges upon their ability to favorably interact with the biological environment (both systemically and locally) and recognize the diseased target tissue. The immune system, composed of a highly coordinated organization of cells trained to recognize foreign bodies, represents a key mediator of these interactions. Although components of this system may act as a barrier to nanoparticle (NP) delivery, the immune system can also be exploited to target and trigger signaling cues that facilitate the therapeutic response stemming from systemic administration of NPs. The nano-bio interface represents the key facilitator of this communication exchange, where the surface properties of NPs govern their

Indexed as

biomimetic nanoparticlesdrug deliveryimmune systemimmunomodulationnano-bio interface

Identifiers

PMID32626700
PMCPMC7311577

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.