Evidence map›Paper›PMID 32626543›Full record

ArticleDisease markers2020

Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients.

Han Shuwen, Yang Xi, Da Miao, Xu Jiamin, Zhuang Jing, Gao Weili

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Han ShuwenDepartment of Oncology, Huzhou Cent Hosp, Affiliated Cent Hosp Huzhou University, 198 Hongqi Rd, Huzhou, Zhejiang, China.ORCID https://orcid.org/0000-0001-6180-9565
Yang XiDepartment of Oncology, Huzhou Central Hospital, 198 Hongqi Road, Huzhou, Zhejiang Province 313000, China.
Da MiaoDepartment of Nursing, Huzhou Third Municipal Hospital, No. 2088 East Tiaoxi Road, Huzhou, Zhejiang Province 313000, China.ORCID https://orcid.org/0000-0002-9283-279X
Xu JiaminGraduate School of Nursing, Huzhou University, No. 1 Bachelor Road, Huzhou, Zhejiang Province 313000, China.
Zhuang JingGraduate School of Nursing, Huzhou University, No. 1 Bachelor Road, Huzhou, Zhejiang Province 313000, China.
Gao WeiliDepartment of Thyroid Surgery, Huzhou Central Hospital, No. 198 Hongqi Road, Huzhou, Zhejiang Province 313000, China.ORCID https://orcid.org/0000-0002-4885-4203
Huzhou University · CNHuzhou Central Hospital · CNThird People's Hospital of Huzhou · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThyroid carcinoma (THCA) is one of the most common malignancies of the endocrine system, which is usually treated by surgery combined with iodine-131 (I

aimsThis study is aimed at exploring the potential targets of I

methodsThe RNA-sequencing data of THCA in The Cancer Genome Atlas database (including 568 THCA samples) was downloaded. The differentially expressed genes (DEGs) between the tumour samples whether or not subjected to I

resultsThere were 500 DEGs (167 upregulated and 333 downregulated) between the two groups. WGCNA analysis showed that the green module (428 nodes) exhibited the most significant correlation with I

conclusionI

Indexed as

Computational BiologyDatabases, GeneticData MiningGene Expression ProfilingGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansIodine RadioisotopesProtein Interaction MapsSequence Analysis, RNAThyroid NeoplasmsIodine-131Iodine Radioisotopes

Identifiers

PMID32626543
PMCPMC7317313
OpenAlexW3036439355

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.