Evidence map›Paper›PMID 32626148›Full record

ArticleEFSA journal. European Food Safety Authority2019

Re-evaluation of benzyl alcohol (E 1519) as food additive.

EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Karl-Heinz Engel, Paul Fowler, Peter Fürst, Rainer Gürtler, Ursula Gundert-Remy, Trine Husøy and 17 more

Open access · diamondAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Safety and efficacy of a feed additive consisting of an essential oil fromEFSA journal. European Food Safety Authority · 2022
    Article
  12. Article
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  15. Article
  16. Selective Extraction of Piceatannol fromInternational journal of molecular sciences · 2021
    Article
  17. Article
  18. Re-evaluation of benzyl alcohol (E 1519) as food additive.EFSA journal. European Food Safety Authority · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

EFSA Panel on Food Additives and Flavourings (FAF)
Maged Younes
Gabriele Aquilina
Laurence Castle
Karl-Heinz Engel
Paul Fowler
Peter Fürst
Rainer Gürtler
Ursula Gundert-Remy
Trine Husøy
Wim Mennes
Peter Moldeus
Agneta Oskarsson
Romina Shah
Ine Waalkens-Berendsen
Detlef Wölfle
Polly Boon
Riccardo Crebelli
Alessandro Di Domenico
Metka Filipič
Alicja Mortensen
Henk Van Loveren
Ruud Woutersen
Petra Gergelova
Alessandra Giarola
Federica Lodi
Maria Jose Frutos Fernandez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Panel on Food Additives and Flavourings (FAF) provided a scientific opinion re-evaluating the safety of benzyl alcohol (E 1519) when used as a food additive. The Panel considered that adequate exposure and toxicity data were available. Benzyl alcohol (E 1519) is authorised as a food additive in the EU in accordance with Annex III to Regulation (EC) No 1333/2008. The Panel considered benzyl alcohol of low acute toxicity with no concern with respect to genotoxicity and carcinogenicity and established an acceptable daily intake (ADI) of 4 mg/kg body weight (bw) per day based on a no observable adverse effect level (NOAEL) of 400 mg/kg bw per day from the carcinogenicity study in rats. The mean and high exposure estimates in the refined exposure scenarios were maximally 0.27 and 0.81 mg/kg bw per day in toddlers, respectively. The exposure estimates to benzyl alcohol (E 1519) were below the ADI of 4 mg/kg bw per day in all population groups. The Panel noted that also the exposure in the

Indexed as

acceptable daily intakebenzyl alcoholdietary exposureE 1519food additiverisk assessmentsafety

Identifiers

PMID32626148
PMCPMC7008871
OpenAlexW2982492120

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.