Evidence map›Paper›PMID 32625639›Full record

ArticleEFSA journal. European Food Safety Authority2017

Scientific opinion of Flavouring Group Evaluation 502 (FGE.502): grill flavour 'Grillin' 5078'.

EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Vittorio Silano, Claudia Bolognesi, Laurence Castle, Kevin Chipman, Jean-Pierre Cravedi, Karl-Heinz Engel, Paul Fowler, Roland Franz, Konrad Grob and 24 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
Vittorio Silano
Claudia Bolognesi
Laurence Castle
Kevin Chipman
Jean-Pierre Cravedi
Karl-Heinz Engel
Paul Fowler
Roland Franz
Konrad Grob
Rainer Gürtler
Trine Husøy
Sirpa Kärenlampi
Maria Rosaria Milana
Karla Pfaff
Gilles Riviere
Jannavi Srinivasan
Maria de Fátima Tavares Poças
Christina Tlustos
Detlef Wölfle
Holger Zorn
Ulla Beckman Sundh
Romualdo Benigni
Mona-Lise Binderup
Leon Brimer
Francesca Marcon
Daniel Marzin
Pasquale Mosesso
Gerard Mulder
Agneta Oskarsson
Camilla Svendsen
Maria Carfì
Carla Martino
Wim Mennes

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF Panel) was requested to deliver a scientific opinion on the implication for human health of the product Grillin' 5078 [FL-no: 21.003] in the Flavouring Group Evaluation 502, according to Regulation (EC) No 1331/2008 and Regulation (EC) No 1334/2008 of the European Parliament and of the Council. The product is derived from heat-treated high oleic sunflower oil and intended to be used as a food flavouring with charbroiled or grilled aroma in a wide variety of food categories either in liquid or powder form. Information on manufacturing and compositional data was considered adequate to show the reproducibility of the production process. However, the Panel noted that a considerable amount of the non-volatile fraction of the product could not be identified. The chronic dietary exposure to the substance estimated using the Added Portions Exposure Technique (APET) was calculated to be 60 mg/person per day for a 60-kg adult and 37.8 mg/person per day for a 15-kg child. The data submitted for evaluating the genotoxic potential of the flavouring was considered insufficient. There are still 12 substances in the flavouring for which the evaluation of genotoxic potential is pending. No toxicity studies have been provided on the final product itself. Only information on a number of constituents of the flavouring and data on toxicity of several thermally treated fats and oils were provided by the applicant. However, the Panel considered the time-temperature conditions that were applied in the preparation of the substances tested as not comparable to those applied in the course of the production of the flavouring. The Panel concluded that on the basis of the data provided by the applicant the safety of Grillin' 5078 cannot be established.

Indexed as

complex mixtureFGE.502FL‐no: 21.003Grillin’ 5078other flavouring

Identifiers

PMID32625639
PMCPMC7009981

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.