Evidence map›Paper›PMID 32625486›Full record

ArticleEFSA journal. European Food Safety Authority2017

Dietary reference values for vitamin K.

EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Dominique Turck, Jean-Louis Bresson, Barbara Burlingame, Tara Dean, Susan Fairweather-Tait, Marina Heinonen, Karen Ildico Hirsch-Ernst, Inge Mangelsdorf, Harry J McArdle and 18 more

Registry-linked trialAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04939636 (The Influence of Vitamin D on the Physical Performance and General Health of Conscripts of the Estonian Defence Forces), which is not on this map. Cited by 127 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04939636 nacompletednot on this mapstarted 2021, after this paper: background citation

The Influence of Vitamin D on the Physical Performance and General Health of Conscripts of the Estonian Defence Forces

TypeinterventionalSponsorTartu University HospitalRan2021 to 2022Enrolled112ConditionsVitamin D Deficiency, Military Activity, Physical StressArmsVitamin D3 capsules 4000IU/100µg., Vitamin D3 capsules 600IU/15µg.
3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Vitamin D supplementation for women during pregnancy.The Cochrane database of systematic reviews · 2024
    Pooled it
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  5. Vitamin D supplementation for women during pregnancy.The Cochrane database of systematic reviews · 2019
    Pooled it
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67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
Dominique Turck
Jean-Louis Bresson
Barbara Burlingame
Tara Dean
Susan Fairweather-Tait
Marina Heinonen
Karen Ildico Hirsch-Ernst
Inge Mangelsdorf
Harry J McArdle
Androniki Naska
Grażyna Nowicka
Kristina Pentieva
Yolanda Sanz
Alfonso Siani
Anders Sjödin
Martin Stern
Daniel Tomé
Henk Van Loveren
Marco Vinceti
Peter Willatts
Christel Lamberg-Allardt
Hildegard Przyrembel
Inge Tetens
Céline Dumas
Lucia Fabiani
Sofia Ioannidou
Monika Neuhäuser-Berthold

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derives dietary reference values (DRVs) for vitamin K. In this Opinion, the Panel considers vitamin K to comprise both phylloquinone and menaquinones. The Panel considers that none of the biomarkers of vitamin K intake or status is suitable by itself to derive DRVs for vitamin K. Several health outcomes possibly associated with vitamin K intake were also considered but data could not be used to establish DRVs. The Panel considers that average requirements and population reference intakes for vitamin K cannot be derived for adults, infants and children, and therefore sets adequate intakes (AIs). The Panel considers that available evidence on occurrence, absorption, function and content in the body or organs of menaquinones is insufficient, and, therefore, sets AIs for phylloquinone only. Having assessed additional evidence available since 1993 in particular related to biomarkers, intake data and the factorial approach, which all are associated with considerable uncertainties, the Panel maintains the reference value proposed by the Scientific Committee for Food (SCF) in 1993. An AI of 1 μg phylloquinone/kg body weight per day is set for all age and sex population groups. Considering the respective reference body weights, AIs for phylloquinone are set at 70 μg/day for all adults including pregnant and lactating women, at 10 μg/day for infants aged 7-11 months, and between 12 μg/day for children aged 1-3 years and 65 μg/day for children aged 15-17 years.

Indexed as

Adequate IntakeDietary Reference Valuemenaquinonesphylloquinonevitamin K

Identifiers

PMID32625486
PMCPMC7010012

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.