Evidence map›Paper›PMID 32625397›Full record

ArticleEFSA journal. European Food Safety Authority2017

Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species.

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Guido Rychen, Gabriele Aquilina, Giovanna Azimonti, Vasileios Bampidis, Maria de Lourdes Bastos, Georges Bories, Pier Sandro Cocconcelli, Gerhard Flachowsky, Jürgen Gropp and 19 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Evaluating the consistency of judgments derived through both in silico and expert application of the Cramer classification scheme.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Antioxidant, Antidiabetic, and Antibacterial Potentials and Chemical Composition ofAdvances in pharmacological and pharmaceutical sciences · 2022
    Article
  7. Volatile Organic Compounds FromFrontiers in microbiology · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Guido Rychen
Gabriele Aquilina
Giovanna Azimonti
Vasileios Bampidis
Maria de Lourdes Bastos
Georges Bories
Pier Sandro Cocconcelli
Gerhard Flachowsky
Jürgen Gropp
Boris Kolar
Maryline Kouba
Secundino López Puente
Marta López-Alonso
Alberto Mantovani
Baltasar Mayo
Fernando Ramos
Maria Saarela
Roberto Edoardo Villa
Robert John Wallace
Pieter Wester
Paul Brantom
Birgit Dusemund
Christer Hogstrand
Patrick Van Beelen
Johannes Westendorf
Lucilla Gregoretti
Paola Manini
Andrew Chesson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 22 compounds belonging to chemical group 24 (pyrazine derivatives). They are currently authorised as flavours in food. The FEEDAP Panel concludes that: 2,3-diethylpyrazine [14.005], 2-ethyl-3-methylpyrazine [14.006], 5,6,7,8-tetrahydroquinoxaline [14.015], 2,3,5,6-tetramethylpyrazine [14.018], 2,3,5-trimethylpyrazine [14.019], 2,5-dimethylpyrazine [14.020], 2,6-dimethylpyrazine [14.021], 2-ethylpyrazine [14.022], 2-ethyl-3,5-dimethylpyrazine [14.024], 2,5 or 6-methoxy-3-methylpyrazine [14.025], 2-methylpyrazine [14.027], acetylpyrazine [14.032], 6,7-dihydro-5-methyl-5

Indexed as

chemical group 24pyrazine derivativessafetysensory additives

Identifiers

PMID32625397
PMCPMC7009992

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.