Evidence map›Paper›PMID 32625343›Full record

ArticleEFSA journal. European Food Safety Authority2017

Re-evaluation of alginic acid and its sodium, potassium, ammonium and calcium salts (E 400-E 404) as food additives.

EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), Maged Younes, Peter Aggett, Fernando Aguilar, Riccardo Crebelli, Metka Filipič, Maria Jose Frutos, Pierre Galtier, David Gott, Ursula Gundert-Remy and 18 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03901157 (The Effect of Repetitive Intake of Lipids in Alginate Gel on Food Intake and Satiety), which is not on this map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03901157 naunknown statusnot on this mapstarted 2019, after this paper: background citation

The Effect of Repetitive Intake of Lipids in Alginate Gel on Food Intake and Satiety

TypeinterventionalSponsorMaastricht University Medical CenterRan2019 to 2020Enrolled44ConditionsSatiation, Overweight and Obesity, Satiety ResponseArmsYogurt A: Active, Yogurt B: Control
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 73 citations in OpenAlex.

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  15. Frontiers in nutrition · 2023
    Article
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  19. Review
  20. Alginate and alginate composites for biomedical applications.Asian journal of pharmaceutical sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
Maged Younes
Peter Aggett
Fernando Aguilar
Riccardo Crebelli
Metka Filipič
Maria Jose Frutos
Pierre Galtier
David Gott
Ursula Gundert-Remy
Gunter Georg Kuhnle
Claude Lambré
Jean-Charles Leblanc
Inger Therese Lillegaard
Peter Moldeus
Alicja Mortensen
Agneta Oskarsson
Ivan Stankovic
Ine Waalkens-Berendsen
Rudolf Antonius Woutersen
Matthew Wright
Leon Brimer
Oliver Lindtner
Pasquale Mosesso
Anna Christodoulidou
Zsuzsanna Horváth
Federica Lodi
Birgit Dusemund

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present opinion deals with the re-evaluation of alginic acid and its sodium, potassium, ammonium and calcium salts (E 400-E 404) when used as food additives. Alginic acid and its salts (E 400-E 404) are authorised food additives in the EU in accordance with Annex II and Annex III to Regulation (EC) No 1333/2008. Following the conceptual framework for the risk assessment of certain food additives re-evaluated under Commission Regulation (EU) No 257/2010, the Panel concluded that there was no need for a numerical Acceptable Daily Intake (ADI) for alginic acid and its salts (E 400, E 401, E 402, E 403 and E 404), and that there was no safety concern at the level of the refined exposure assessment for the reported uses of alginic acid and its salts (E 400, E 401, E 402, E 403 and E 404) as food additives. The Panel further concluded that exposure of infants and young children to alginic acid and its salts (E 400, E 401, E 402, E 403 and E 404) by the use of these food additives should stay below therapeutic dosages for these population groups at which side-effects could occur. Concerning the use of alginic acid and its salts (E 400, E 401, E 402, E 403 and E 404) in 'dietary foods for special medical purposes and special formulae for infants' (Food category 13.1.5.1) and 'in dietary foods for babies and young children for special medical purposes as defined in Directive 1999/21/EC' (Food category 13.1.5.2), the Panel further concluded that the available data did not allow an adequate assessment of the safety of alginic acid and its salts (E 400, E 401, E 402, E 403 and E 404) in infants and young children consuming the food belonging to the categories 13.1.5.1 and 13.1.5.2.

Indexed as

alginic acid (E 400)ammonium alginate (E 403)calcium alginate (E 404)food additives.potassium alginate (E 402)sodium alginate (E 401)

Identifiers

PMID32625343
PMCPMC7010146
OpenAlexW2767910065

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.