Evidence map›Paper›PMID 32625123›Full record

ArticleFrontiers in psychiatry2020

Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.

Sven Haufe, Kai G Kahl, Arno Kerling, Gudrun Protte, Pauline Bayerle, Hedwig T Stenner, Simone Rolff, Thorben Sundermeier, Julian Eigendorf, Momme Kück and 11 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03293264 (Effects of a Workplace Health Service Program in Employees With Diagnosed Metabolic Syndrome), which is not on this map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03293264 nacompletednot on this map

Effects of a Workplace Health Service Program in Employees With Diagnosed Metabolic Syndrome

TypeinterventionalSponsorHannover Medical SchoolRan2017 to 2023Enrolled314ConditionsMetabolic SyndromeArmsExercise training group
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Metabolic Syndrome and Psychological Effects of Exercise in Hemodialysis Patients.International journal of environmental research and public health · 2021
    Trial
  5. Review
  6. Review
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Sven HaufeInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Kai G KahlDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.
Arno KerlingInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Gudrun ProtteInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Pauline BayerleInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Hedwig T StennerInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Simone RolffInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Thorben SundermeierInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Julian EigendorfInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Momme KückInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Alexander A HankeInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Katriona Keller-VaradyInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Ralf EnsslenVolkswagen AG, Wolfsburg, Germany.
Lars NachbarVolkswagen AG, Wolfsburg, Germany.
Dirk LauensteinAudi BKK Health Insurance, Ingolstadt, Germany.
Dietmar BöthigDepartment of Cardiac, Thoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Christoph TerkampDepartment of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Meike StieschDepartment of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Denise Hilfiker-KleinerDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Axel HaverichDepartment of Cardiac, Thoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Uwe TegtburInstitute of Sports Medicine, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DEVolkswagen Group (Germany) · DEKlinikum Ingolstadt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor depressive disorder and anxiety disorders are associated with less productivity, earlier retirement, and more sick-days at the workplace. These associations also exist for patients with metabolic syndrome. For both, exercise is a generally recommended part of multimodal treatments. However, for individuals with metabolic syndrome, in which depression and anxiety is more prevalent and severe, evidence for the efficacy of exercise interventions is limited.

methodsCompany employees with diagnosed metabolic syndrome (n=314, age: 48 ± 8 yrs) were randomized to a 6-month exercise intervention (150 min per week) or wait-list control. Participants received individual recommendations for exercise activities by personal meetings, telephone, or

resultsWe included 314 subjects from which 287 finished the intervention. Total work ability, depression- and anxiety severity, and the mental component score of the SF-36 improved after 6 months exercise compared to controls. After baseline stratification for normal (HADS scores 0-7) and increased depression- and anxiety scores (HADS scores 8-21) individuals with increased severity scores had similar age, body composition, blood lipids, and cardiorespiratory fitness compared to those with normal scores, but lower total work ability and component sum scores of health-related quality of life. After 6 months total work ability increased in the exercise group compared to controls with the magnitude of the observed increase being significantly greater for subjects with increased depression- and anxiety severity at baseline compared to those with normal severity scores.

conclusionsA 6-month exercise intervention for company employees with metabolic syndrome showed strongest effects on self-perceived work ability in individuals with mild to severe depression- and anxiety severity. This suggests exercise programs offered to workers with metabolic syndrome not only reduces individual disease risk but may also reduce healthcare and employers costs arising from metabolic syndrome and mental disease conditions. CLINICAL

trial registrationClinicalTrials.gov, identifier NCT03293264.

Indexed as

activity devicesmental healthphysical activityproductivitytelemonitoring

Identifiers

PMID32625123
PMCPMC7314973
OpenAlexW3036308709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.