Evidence map›Paper›PMID 32625098›Full record

ArticleFrontiers in pharmacology2020

Hypokalemia After Rituximab Administration in Steroid-Dependent Nephrotic Syndrome: A Case Report.

Francesco Guzzi, Mattia Giovannini, Carmela Errichiello, Giulia Liccioli, Francesca Mori, Rosa Maria Roperto, Paola Romagnani

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francesco GuzziNephrology and Dialysis Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Mattia GiovanniniAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Carmela ErrichielloNephrology and Dialysis Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Giulia LiccioliAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Francesca MoriAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Rosa Maria RopertoNephrology and Dialysis Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Paola RomagnaniNephrology and Dialysis Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Meyer Children's Hospital · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The monoclonal antibody rituximab is a commonly used steroid sparing agent for steroid-dependent idiopathic nephrotic syndrome of childhood. With this brief report, we describe the first case of symptomatic hypokalemia after intravenous rituximab administration in a young woman. The sudden onset of dizziness and palpitation prompted acute life-threatening hypokalemia recognition by blood gas analysis and electrocardiography. Her symptoms were rapidly controlled by intravenous potassium administration. Such adverse drug reactions, when mild and self-limiting, can easily be overlooked if not expected or investigated. Health professionals should take into account the possibility of acute hypokalemia after rituximab administration in order to promptly setup the appropriate treatment and limit potentially severe complications.

Indexed as

adverse drug reactionsbiologic drugscase reportkalemianephrology

Identifiers

PMID32625098
PMCPMC7311762
OpenAlexW3036463535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.