Evidence map›Paper›PMID 32625025›Full record

ArticleEngineering in life sciences2019

CRISPR-based curing and analysis of metabolic burden of cryptic plasmids in

Halimatun S Zainuddin, Yanfen Bai, Thomas J Mansell

Open access · bronzeAbstract read
In one paragraph

Article in Engineering in life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. An Engineered Variant ofACS synthetic biology · 2026
    Article
  6. Article
  7. EngineeredActa pharmaceutica Sinica. B · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Pharmaceutics · 2021
    Review
  16. Plasmid Vectors forACS synthetic biology · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Halimatun S ZainuddinDepartment of Chemical and Biological Engineering Iowa State University Sweeney Hall Ames IA USA.
Yanfen BaiDepartment of Chemical and Biological Engineering Iowa State University Sweeney Hall Ames IA USA.
Thomas J MansellDepartment of Chemical and Biological Engineering Iowa State University Sweeney Hall Ames IA USA.ORCID https://orcid.org/0000-0001-8807-4570
Iowa State University · US

Funding

Co-culture of probiotic bacteria for growth factor delivery in minigut organoidsR21GM131189 · NIGMS · IOWA STATE UNIVERSITY · PI MANSELL, THOMAS J · 2018 to 2019
$391k
NIGMS NIH HHS R21 GM131189
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

genetic stabilityheterologous protein expressionlive biotherapeuticsmetabolic engineeringprobiotics

Identifiers

PMID32625025
PMCPMC6999193
OpenAlexW2946737116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.