ArticleEngineering in life sciences2019
Carbon nanotube/polyurethane modified hollow fiber-pencil graphite electrode for in situ concentration and electrochemical quantification of anticancer drugs Capecitabine and Erlotinib.
Article in Engineering in life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 21 citations in OpenAlex.
- Titanium dioxide nanoparticle-modified screen-printed electrode for erlotinib determination.ADMET & DMPK · 2026Article
- A Mini Review on Electrochemical Nano-biosensors in Detection of Drugs/Pesticides.Indian journal of microbiology · 2025Article
- Recent Biomedical Applications of Coupling Nanocomposite Polymeric Materials Reinforced with Variable Carbon Nanofillers.Biomedicines · 2023Review
- Carbon nanotube/polyurethane modified hollow fiber-pencil graphite electrode for in situ concentration and electrochemical quantification of anticancer drugs Capecitabine and Erlotinib.Engineering in life sciences · 2019Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
A sensitive electrochemical sensor has been designed for in situ preconcentration and determination of anticancer drugs Capecitabine (CPT) and Erlotinib hydrochloride (ETHC) based on a pencil graphite electrode modified with multivalued carbon nanotube-polyurethane (MWCNT-PUFIX) nanocomposite that was supported with a piece of polypropylene hollow fiber (HF-PGE). The electrochemical behavior of CPT and ETHC on the MWCNT-PUFIX/HF-PGE modified electrode was investigated by differential pulse voltammetry (DPV) techniques and the obtained results confirmed its efficiency for sensing of CPT and ETHC. The synthesized nanocomposite was characterized by infrared spectroscopy and scanning electron microscope. After optimization of some effective parameters on the method efficiency including pH, nanocomposite amount, the type of organic solvent, scan rate and the effect of some additives, the mentioned sensor presented suitable results for determination of CPT and ETHC with the linear ranges from 7.70 to 142.00 μM and 0.11 to 23.50 μM and detection limits of 0.11 and 0.02 μM, respectively. Also, the fabricated sensor has shown good performance in analysis of CPT and ETHC in biological samples.
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