ArticleEngineering in life sciences2019
An electrochemical biosensor for prostate cancer biomarker detection using graphene oxide-gold nanostructures.
Article in Engineering in life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 97 citations in OpenAlex.
- New Perspective on Functionalized Metal Nanoparticles and Two-Dimensional Nanomaterials-Based Composites for Electrochemical Biomarker Sensing and Energy Storage Devices.Chemical record (New York, N.Y.) · 2026Review
- Integrative advances in biomarker-driven prostate cancer management from genomic discovery to precision oncology.Discover oncology · 2026Review
- ITO-PET electrochemical biosensor functionalized with carboxylated graphene oxide for prostate cancer biomarker detection.Scientific reports · 2026Article
- The progress of biomarkers detection to lung cancer.Discover oncology · 2026Review
- Highly sensitive and selective detection of KLK4 in human serum with a low-cost electrochemical biosensor.Turkish journal of chemistry · 2025Article
- Article
- Real-Time and Ultrasensitive Prostate-Specific Antigen Sensing Using Love-Mode Surface Acoustic Wave Immunosensor Based on MoSSensors (Basel, Switzerland) · 2024Article
- Integration of nanobiosensors into organ-on-chip systems for monitoring viral infections.Nano convergence · 2024Review
- Label-Free Detection of CA19-9 Using a BSA/Graphene-Based Antifouling Electrochemical Immunosensor.Sensors (Basel, Switzerland) · 2023Article
- Nanoribbon Biosensor-Based Detection of microRNA Markers of Prostate Cancer.Sensors (Basel, Switzerland) · 2023Article
- Ultrasensitive Electrochemical Immunosensors Using Nanobodies as Biocompatible Sniffer Tools of Agricultural Contaminants and Human Disease Biomarkers.Micromachines · 2023Review
- Recent Trends in Metal Nanoparticles Decorated 2D Materials for Electrochemical Biomarker Detection.Biosensors · 2023Review
- Recent Progress in Biosensors for Detection of Tumor Biomarkers.Molecules (Basel, Switzerland) · 2022Review
- Current Perspectives in Graphene Oxide-Based Electrochemical Biosensors for Cancer Diagnostics.Biosensors · 2022Review
- Properties and Applications of Graphene and Its Derivatives in Biosensors for Cancer Detection: A Comprehensive Review.Biosensors · 2022Review
- Graphene-Based Biosensors for Molecular Chronic Inflammatory Disease Biomarker Detection.Biosensors · 2022Review
- Highly Sensitive Detection of Carcinoembryonic AntigenFrontiers in chemistry · 2022Article
- Multiplexed Prostate Cancer Companion Diagnostic Devices.Sensors (Basel, Switzerland) · 2021Review
- Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers.Frontiers in chemistry · 2021Review
- A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID-19 and Other Viruses.Advanced materials (Deerfield Beach, Fla.) · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper, a most sensitive electrochemical biosensor for detection of prostate-specific antigen (PSA) was designed. To reach the goal, a sandwich type electrode composed of reduced graphene oxide/ gold nanoparticles (GO/AuNPs), Anti-Total PSA monoclonal antibody, and anti-Free PSA antibody was assembled. The functionalized materials were thoroughly characterized by atomic force microscope spectroscopy, transmission electron microscopy, and X-ray diffraction techniques. The electrochemical properties of each of the modification step were evaluated by cyclic voltammetry and electrochemical impedance spectroscopy. The results presented that the proposed biosensor possesses high sensitivity toward total and free PSA. Furthermore, the fabricated biosensor revealed an excellent selectivity for PSA in comparison to the other tumor markers such as BHCG, Alb, CEA, CA125, and CA19-9. The limit of detection for the proposed electrochemical biosensor was estimated to be around 0.2 and 0.07 ng/mL for total and free PSA antigen, respectively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.