Evidence map›Paper›PMID 32624987›Full record

ArticleEngineering in life sciences2019

Characterization and potential antitumor effect of a heteropolysaccharide produced by the red alga

Biliana Nikolova, Severina Semkova, Iana Tsoneva, Georgi Antov, Juliana Ivanova, Ivanina Vasileva, Proletina Kardaleva, Ivanka Stoineva, Nelly Christova, Lilyana Nacheva and 1 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Engineering in life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Biliana NikolovaInstitute of Biophysics and Biomedical Engineering Bulgarian Academy of Sciences Sofia Bulgaria.
Severina SemkovaInstitute of Biophysics and Biomedical Engineering Bulgarian Academy of Sciences Sofia Bulgaria.
Iana TsonevaInstitute of Biophysics and Biomedical Engineering Bulgarian Academy of Sciences Sofia Bulgaria.
Georgi AntovInstitute of Biophysics and Biomedical Engineering Bulgarian Academy of Sciences Sofia Bulgaria.
Juliana IvanovaInstitute of Plant Physiology and Genetics Bulgarian Academy of Sciences Sofia Bulgaria.
Ivanina VasilevaInstitute of Plant Physiology and Genetics Bulgarian Academy of Sciences Sofia Bulgaria.
Proletina KardalevaInstitute of Organic Chemistry with Centre of Phytochemistry Bulgarian Academy of Sciences Sofia Bulgaria.
Ivanka StoinevaInstitute of Organic Chemistry with Centre of Phytochemistry Bulgarian Academy of Sciences Sofia Bulgaria.
Nelly ChristovaThe Stephan Angeloff Institute of Microbiology Bulgarian Academy of Sciences Sofia Bulgaria.
Lilyana NachevaThe Stephan Angeloff Institute of Microbiology Bulgarian Academy of Sciences Sofia Bulgaria.
Lyudmila KabaivanovaThe Stephan Angeloff Institute of Microbiology Bulgarian Academy of Sciences Sofia Bulgaria.
Institute of Biophysics and Biomedical Engineering · BGStephan Angeloff Institute of Microbiology · BGBulgarian Academy of Sciences · BGInstitute of Plant Physiology and Genetics · BGInstitute of Organic Chemistry with Centre of Phytochemistry · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Taking into account the rising trend of the incidence of cancers of various organs, effective therapies are urgently needed to control human malignancies. However, almost all chemotherapy drugs currently on the market cause serious side effects. Fortunately, several studies have shown that some non-toxic biological macromolecules, including algal polysaccharides, possess anti-cancer activities or can increase the efficacy of conventional chemotherapy drugs. Polysaccharides are characteristic secondary metabolites of many algae. The efficacy of polysaccharides on the normal and cancer cells is not well investigated, but our investigations proved a cell specific effect of a newly isolated extracellular polysaccharide from the red microalga

Indexed as

algal heteropolysaccharideantitumor effectPorphyridium sordidum

Identifiers

PMID32624987
PMCPMC6999067
OpenAlexW2953429679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.