Evidence map›Paper›PMID 32624919›Full record

ReviewEngineering in life sciences2018

New approaches in bioprocess-control: Consortium guidance by synthetic cell-cell communication based on fungal pheromones.

Stefan Hennig, Mandy Wenzel, Christiane Haas, Andreas Hoffmann, Jost Weber, Gerhard Rödel, Kai Ostermann

Open access · bronzeAbstract readReview
In one paragraph

Review in Engineering in life sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Stefan HennigInstitute of Genetics Technische Universität Dresden Dresden Germany.
Mandy WenzelInstitute of Genetics Technische Universität Dresden Dresden Germany.
Christiane HaasInstitute of Natural Materials Technology Technische Universität Dresden Dresden Germany.
Andreas HoffmannInstitute of Natural Materials Technology Technische Universität Dresden Dresden Germany.
Jost WeberInstitute of Natural Materials Technology Technische Universität Dresden Dresden Germany.
Gerhard RödelInstitute of Genetics Technische Universität Dresden Dresden Germany.
Kai OstermannInstitute of Genetics Technische Universität Dresden Dresden Germany.
TU Dresden · DEEvolva (Denmark) · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioconversions in industrial processes are currently dominated by single-strain approaches. With the growing complexity of tasks to be carried out, microbial consortia become increasingly advantageous and eventually may outperform single-strain fermentations. Consortium approaches benefit from the combined metabolic capabilities of highly specialized strains and species, and the inherent division of labor reduces the metabolic burden for each strain while increasing product yields and reaction specificities. However, consortium-based designs still suffer from a lack of available tools to control the behavior and performance of the individual subpopulations and of the entire consortium. Here, we propose to implement novel control elements for microbial consortia based on artificial cell-cell communication

Indexed as

Bioprocess‐controlCell‐cell communicationFungal pheromoneSensor‐actor systems

Identifiers

PMID32624919
PMCPMC6999462
OpenAlexW2789847940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.