Evidence map›Paper›PMID 32624838›Full record

ArticleEngineering in life sciences2017

Bioproduction of α-humulene in metabolically engineered

Semra Alemdar, Jan C König, Steffen Hartwig, Thore Frister, Thomas Scheper, Sascha Beutel

Open access · bronzeAbstract read
In one paragraph

Article in Engineering in life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Bioproduction of Linalool From Paper Mill Waste.Frontiers in bioengineering and biotechnology · 2022
    Article
  6. Article
  7. Article
  8. Substrate specificity of α-humulene synthase fromEngineering in life sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Semra AlemdarLeibniz University Hannover Institute of Technical Chemistry Hannover Germany.ORCID 0000-0001-7336-7194
Jan C KönigLeibniz University Hannover Institute of Technical Chemistry Hannover Germany.
Steffen HartwigLeibniz University Hannover Institute of Technical Chemistry Hannover Germany.
Thore FristerLeibniz University Hannover Institute of Technical Chemistry Hannover Germany.
Thomas ScheperLeibniz University Hannover Institute of Technical Chemistry Hannover Germany.
Sascha BeutelLeibniz University Hannover Institute of Technical Chemistry Hannover Germany.
Leibniz University Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zerumbone is a sesquiterpene ketone with potent anti-cancerogenic activities, produced in several ginger species of the Zingiberaceae familiy. We have investigated the biotechnological production of α-humulene, a precursor of zerumbone. By implementing a heterologous mevalonate pathway in combination with the α-humulene synthase expression, we effectively synthesized α-humulene from glucose in

Indexed as

Allylic oxidationIn situ product recoveryIntegrated bioprocessSemi‐synthesisZerumbone

Identifiers

PMID32624838
PMCPMC6999591
OpenAlexW2624188796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.