Evidence map›Paper›PMID 32624756›Full record

ArticleEngineering in life sciences2017

Characterization and high-yield production of non-

Weihua Hou, Xianchao Meng, Yuxiong Wang, Wei Mo, Yi Wu, Min Yu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Engineering in life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Carbon metabolism influenced for promoters and temperature used in the heterologous protein production using Pichia pastoris yeast.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Weihua HouMinistry of Education and Department of Biochemistry and Molecular Biology School of Basic Medicine Fudan University Shanghai China.
Xianchao MengMinistry of Education and Department of Biochemistry and Molecular Biology School of Basic Medicine Fudan University Shanghai China.
Yuxiong WangMinistry of Education and Department of Biochemistry and Molecular Biology School of Basic Medicine Fudan University Shanghai China.
Wei MoMinistry of Education and Department of Biochemistry and Molecular Biology School of Basic Medicine Fudan University Shanghai China.
Yi WuMinistry of Education and Department of Biochemistry and Molecular Biology School of Basic Medicine Fudan University Shanghai China.
Min YuMinistry of Education and Department of Biochemistry and Molecular Biology School of Basic Medicine Fudan University Shanghai China.
Ministry of Education · KNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B-cell maturation antigen (BCMA) fused at the C-terminus to the Fc portion of human IgG1 (BCMA-Fc) blocks B-cell activating factor (BAFF) and proliferation-inducing ligand (APRIL)-mediated B-cell activation, leading to immune disorders. The fusion protein has been cloned and produced by several engineering cell lines. To reduce cost and enhance production, we attempted to express recombinant human BCMA-Fc (rhBCMA-Fc) in

Indexed as

APRILB‐cell maturation antigenN‐glycosylationPichia pastorisRecombinant human protein

Identifiers

PMID32624756
PMCPMC6999299
OpenAlexW2434268393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.