ArticleEngineering in life sciences2017
Online bioprocess data generation, analysis, and optimization for parallel fed-batch fermentations in milliliter scale.
Article in Engineering in life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Raman-guided sample subset selection for cost-efficient offline calibration in bioprocesses.Bioprocess and biosystems engineering · 2026Article
- Automated high-throughput screening combined with model-assisted analysis enables quantitative identification of process drivers and trade-offs during extracellular Fab production in Escherichia coli.Bioprocess and biosystems engineering · 2026Article
- Droplet based microfluidic and miniaturization at high-throughput level to screening heterologous secondary metabolites in microbes: A critical review.Biotechnology letters · 2025Review
- Automation of a Capillary-Wave Microbioreactor Platform to Enhance Phage Sensitivity Screen Efficiency.Engineering in life sciences · 2025Article
- Closing the loop: establishing an autonomous test-learn cycle to optimize induction of bacterial systems using a robotic platform.Frontiers in bioengineering and biotechnology · 2024Article
- From frozen cell bank to product assay: high-throughput strain characterisation for autonomous Design-Build-Test-Learn cycles.Microbial cell factories · 2023Article
- Control of parallelized bioreactors I: dynamic scheduling software for efficient bioprocess management in high-throughput systems.Bioprocess and biosystems engineering · 2022Article
- Deep reinforcement learning for optimal experimental design in biology.PLoS computational biology · 2022Article
- Miniaturization and 3D Printing of Bioreactors: A Technological Mini Review.Micromachines · 2020Review
- Monitoring bioactive and total antibody concentrations for continuous process control by surface plasmon resonance spectroscopy.Engineering in life sciences · 2019Article
- A FRET-based biosensor for the quantification of glucose in culture supernatants of mL scale microbial cultivations.Microbial cell factories · 2019Article
- Monte Carlo Simulations for the Analysis of Non-linear Parameter Confidence Intervals in Optimal Experimental Design.Frontiers in bioengineering and biotechnology · 2019Article
- Accelerated Bioprocess Development of Endopolygalacturonase-Production withBioengineering (Basel, Switzerland) · 2018Article
- Editorial: Bioprocess Development in the era of digitalization.Engineering in life sciences · 2017Article
- Fast-track development of a lactase production process withEngineering in life sciences · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioprocess development, optimization, and control in mini-bioreactor systems require information about essential process parameters, high data densities, and the ability to dynamically change process conditions. We present an integration approach combining a parallel mini-bioreactor system integrated into a liquid handling station (LHS) with a second LHS for offline analytics. Non-invasive sensors measure pH and DO online. Offline samples are collected every 20 min and acetate, glucose, and OD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.