Evidence map›Paper›PMID 32624726›Full record

ReviewEngineering in life sciences2017

Zero-growth bioprocesses: A challenge for microbial production strains and bioprocess engineering.

Julian Lange, Ralf Takors, Bastian Blombach

Abstract readReview
In one paragraph

Review in Engineering in life sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Metabolic engineering ofSynthetic and systems biotechnology · 2026
    Article
  2. Article
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  6. Vibrio natriegens: Application of a Fast-Growing Halophilic Bacterium.Advances in biochemical engineering/biotechnology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Practical genetic control strategies for industrial bioprocesses.Journal of industrial microbiology & biotechnology · 2022
    Review
  12. Co-Production of Isoprene and Lactate by EngineeredMolecules (Basel, Switzerland) · 2021
    Article
  13. Review
  14. Review
  15. EngineeringEngineering in life sciences · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julian LangeInstitute of Biochemical Engineering University of Stuttgart Stuttgart Germany.
Ralf TakorsInstitute of Biochemical Engineering University of Stuttgart Stuttgart Germany.
Bastian BlombachInstitute of Biochemical Engineering University of Stuttgart Stuttgart Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial fermentation of renewable feedstocks is an established technology in industrial biotechnology. Besides strict aerobic or anaerobic modes of operation, novel innovative and industrially applicable fermentation processes were developed connecting the advantages of aerobic and anaerobic conditions in a combined production approach. As a consequence, rapid aerobic biomass formation to high cell densities and subsequent anaerobic high-yield and zero-growth production is realized. Following this strategy, bioprocesses operating with substantial overall yield and productivity can be obtained. Here, we summarize the current knowledge and achievements in such microbial zero-growth production processes and pinpoint to challenges due to the complex adaptation of the cellular metabolism during the cell's passage from aerobiosis to anaerobiosis.

Indexed as

Anaerobic productionCorynebacterium glutamicumEscherichia coli(micro)Aerobic growthOxygen deprivation

Identifiers

PMID32624726
PMCPMC6999391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.