Evidence map›Paper›PMID 32624472›Full record

Trial reportBMJ open2020

Is reduction of routine radiograph use in patients with distal radius fractures cost effective? Analysis of data from the multicentre, randomised controlled WARRIOR trial.

Pieter van Gerven, Johanna M van Dongen, Sidney M Rubinstein, Marco F Termaat, Mostafa El Moumni, Wietse P Zuidema, Pieta Krijnen, Inger B Schipper, Maurits W van Tulder, WARRIOR trial Study Group and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pieter van GervenTrauma Surgery, Leiden University Medical Center, Leiden, The Netherlands p.van_gerven@lumc.nl.ORCID 0000-0003-0010-1496
Johanna M van DongenHealth Sciences, Faculty of Science, Amsterdam Movement Sciences research institute, Vrije Universiteit, Amsterdam, The Netherlands.
Sidney M RubinsteinHealth Sciences, Faculty of Science, Amsterdam Movement Sciences research institute, Vrije Universiteit, Amsterdam, The Netherlands.
Marco F TermaatTrauma Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Mostafa El MoumniTrauma Surgery, University Medical Center Groningen, Groningen, The Netherlands.
Wietse P ZuidemaTrauma Surgery, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
Pieta KrijnenTrauma Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Inger B SchipperTrauma Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Maurits W van TulderHealth Sciences, Faculty of Science, Amsterdam Movement Sciences research institute, Vrije Universiteit, Amsterdam, The Netherlands.ORCID 0000-0002-7589-8471
WARRIOR trial Study Group
WARRIOR-trial Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the cost effectiveness of a reduced imaging follow-up protocol of distal radius fractures compared with usual care.

designAn economical evaluation conducted alongside a multicentre randomised controlled trial (RCT).

settingFour level-one trauma centres in the Netherlands.

participants341 patients participated (usual care (n=172), reduced imaging (n=169)).

interventionsPatients were randomised to usual care (routine radiography at 1, 2, 6 and 12 weeks) or a reduced imaging strategy (radiographs at 6 and 12 weeks only for a clinical indication). OUTCOME MEASURES: Functional outcome was assessed using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire and quality-adjusted life years (QALYs) using the EuroQol-5Dimensions-3 Levels (EQ-5D-3L). Costs were measured using self-reported questionnaires and medical records, and analysed from a societal perspective. Multiple imputation, seemingly unrelated regression analysis and bootstrapping were used to analyse the data.

resultsClinical overall outcomes of both groups were comparable. The difference in DASH was -2.03 (95% CI -4.83 to 0.77) and the difference in QALYs was 0.025 (95% CI -0.01 to 0.06). Patients in the reduced imaging group received on average 3.3 radiographs (SD: 1.9) compared with 4.2 (SD: 1.9) in the usual care group. Costs for radiographic imaging were significantly lower in the reduced imaging group than in the usual care group (€-48 per patient, 95% CI -68 to -27). There was no difference in total costs between groups (€-401 per patient, 95% CI -2453 to 1251). The incremental cost-effectiveness ratio (ICER) for QALYs was -15 872; the ICER for the DASH was 198. The probability of reduced imaging being cost effective compared with usual care ranged from 0.8 to 0.9 at a willingness to pay of €20 000/QALY to €80 000/QALY.

conclusionsImplementing a reduced imaging strategy in the follow-up of distal radius fractures has a high probability of being cost effective for QALYs, without decreasing functional outcome. We, therefore, recommend imaging only when clinically indicated. TRIAL REGISTRATION NUMBER: The Netherlands trial register (NL4477).

Indexed as

AdultAgedCost-Benefit AnalysisFemaleHumansMaleMiddle AgedNetherlandsPractice Patterns, Physicians'RadiographyRadius FracturesSelf ReportSurveys and Questionnairesfoot & anklehealth economicsorthopaedic & trauma surgeryradiology & imaging

Identifiers

PMID32624472
PMCPMC7337891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.